<p>(A) Representative flow CD56<sup>+</sup>/CD3<sup>-</sup> expression in membranes of NK cells; right image: NK cells were gated and analyzed for TLR2 (TLR2<sup>+</sup>/CD56<sup>+</sup>) expression. (B) Representative histograms showing the MFI levels of TLR2 expression on NK cells from control and patients (LCL and DCL). (C) Quantitation of TLR2 expression on NK cells. □ Non-stimulated cells, ▪ LPG-stimulated cells. Data are representative of healthy controls (n = 21), LCL patients (n = 28) and DCL patients (n = 6). These results are the mean ±SEM. *p≤0.05 was considered significant.</p
<p>TLR2, IFN-γ and TNF-α gene expression in NK cells of healthy controls (n = 5), LCL (n = 6) and DC...
<p>(A and B) Western blot shows TLR1 and TLR6 in NK cells. (C and D) Immunoprecipitations were perfo...
BACKGROUND: Natural killer (NK) cells produce multiple cytokines with potential immune regulatory ro...
<p>(A) Representative flow cytometry dot plot (TLR2 vs. CD56) and histogram of TLR2 expression in NK...
<p>(A) Double immunohistochemistry staining of TLR expression (TLR1, TLR2 and TLR6) on NK cells (CD5...
<p>(A) Cells were stained with CD3-FITC, NK1.1-PE and NKp46-APC. The NK cells isolated from mouse sp...
<p>(A) Ex vivo expansion of peripheral blood NK cells. Figure shows the average results of NK cultur...
<p>Flow cytometry relative quantification of CD56<sup>+</sup> Lin<sup>−</sup> NK cells (first panels...
<p>(A) TNF-α production in peripheral blood [control subjects (n = 21), LCL patients (n = 28) and D...
<p>Cells in whole blood were labeled with antibodies against CD56, CD16, TLR2, TLR4, and TLR9. NK ce...
<p>The intensities of expression of CD56 on cells expressing CD62L, CD16 or KIR was analyzed by flow...
<p>(<b>A</b> and <b>C</b>) Flow cytometric analyses of activation markers on <i>Tlr2</i><sup>−/−</su...
(A) Heatmap of DEGs involved in RLR signaling. Each column represents an individual of the indicated...
<p>Healthy human donor PBMCs were mock or VZV infected with or without IL-2 (200 U/ml) for 2 days th...
<p>Figure shows the NKLR analysis of 3 different donors, as indicated in the left. NK cells were def...
<p>TLR2, IFN-γ and TNF-α gene expression in NK cells of healthy controls (n = 5), LCL (n = 6) and DC...
<p>(A and B) Western blot shows TLR1 and TLR6 in NK cells. (C and D) Immunoprecipitations were perfo...
BACKGROUND: Natural killer (NK) cells produce multiple cytokines with potential immune regulatory ro...
<p>(A) Representative flow cytometry dot plot (TLR2 vs. CD56) and histogram of TLR2 expression in NK...
<p>(A) Double immunohistochemistry staining of TLR expression (TLR1, TLR2 and TLR6) on NK cells (CD5...
<p>(A) Cells were stained with CD3-FITC, NK1.1-PE and NKp46-APC. The NK cells isolated from mouse sp...
<p>(A) Ex vivo expansion of peripheral blood NK cells. Figure shows the average results of NK cultur...
<p>Flow cytometry relative quantification of CD56<sup>+</sup> Lin<sup>−</sup> NK cells (first panels...
<p>(A) TNF-α production in peripheral blood [control subjects (n = 21), LCL patients (n = 28) and D...
<p>Cells in whole blood were labeled with antibodies against CD56, CD16, TLR2, TLR4, and TLR9. NK ce...
<p>The intensities of expression of CD56 on cells expressing CD62L, CD16 or KIR was analyzed by flow...
<p>(<b>A</b> and <b>C</b>) Flow cytometric analyses of activation markers on <i>Tlr2</i><sup>−/−</su...
(A) Heatmap of DEGs involved in RLR signaling. Each column represents an individual of the indicated...
<p>Healthy human donor PBMCs were mock or VZV infected with or without IL-2 (200 U/ml) for 2 days th...
<p>Figure shows the NKLR analysis of 3 different donors, as indicated in the left. NK cells were def...
<p>TLR2, IFN-γ and TNF-α gene expression in NK cells of healthy controls (n = 5), LCL (n = 6) and DC...
<p>(A and B) Western blot shows TLR1 and TLR6 in NK cells. (C and D) Immunoprecipitations were perfo...
BACKGROUND: Natural killer (NK) cells produce multiple cytokines with potential immune regulatory ro...