<p>Sequence positions and frequencies of mutated residues in the FGFR protein are shown. Mutational hotspots for each cancer type are displayed as red dots. SMDs are shown as thicker boxes.</p
<p>A) The number of mutations inside functional and control TFBSs, plotted for each tumour sample in...
Abstract Background Cancer mutations accumulate through replication errors and DNA damage coupled wi...
<p>The upper sequence chromatogram shows the heterozygous missense mutation in exon 14 in <i>FGFR2</...
<p>(A) compares the prevalence with which mutations from a specific cancer type fall within signific...
Distribution of TP53 and FGFR3 somatic mutations in relation to tumor morphology and histology.</p
<p>The locations of the novel p.K660N and p.R203C mutations are marked by red dots. TK1/2: tyrosine ...
<p>(a) Common and unique mutations in the FL library and FR library. (b) Heatmap of the positions of...
<p>(A) The histogram displays the proportions of mutation counts detected at each residue to the tot...
<p>The domain architecture of CFTR is shown with TMD-transmembrane domain, NBD-nucleotide binding do...
Snapshots from the MutaGene server show the results of analysis of EGFR gene with a Pan-cancer model...
<p>A. Frequencies of detected mutations in different exons. B. Mutation distribution in exons. C. Mu...
<p>A. shows the distribution of mutational hotspots for different cancer types within a given domain...
Fibroblast growth factor receptors (FGFRs) are recurrently altered by single nucleotide variants (SN...
Identifying driver mutations and their functional consequences is critical to our understanding of c...
We have investigated the properties of three sets of human missense genetic variations: cancer somat...
<p>A) The number of mutations inside functional and control TFBSs, plotted for each tumour sample in...
Abstract Background Cancer mutations accumulate through replication errors and DNA damage coupled wi...
<p>The upper sequence chromatogram shows the heterozygous missense mutation in exon 14 in <i>FGFR2</...
<p>(A) compares the prevalence with which mutations from a specific cancer type fall within signific...
Distribution of TP53 and FGFR3 somatic mutations in relation to tumor morphology and histology.</p
<p>The locations of the novel p.K660N and p.R203C mutations are marked by red dots. TK1/2: tyrosine ...
<p>(a) Common and unique mutations in the FL library and FR library. (b) Heatmap of the positions of...
<p>(A) The histogram displays the proportions of mutation counts detected at each residue to the tot...
<p>The domain architecture of CFTR is shown with TMD-transmembrane domain, NBD-nucleotide binding do...
Snapshots from the MutaGene server show the results of analysis of EGFR gene with a Pan-cancer model...
<p>A. Frequencies of detected mutations in different exons. B. Mutation distribution in exons. C. Mu...
<p>A. shows the distribution of mutational hotspots for different cancer types within a given domain...
Fibroblast growth factor receptors (FGFRs) are recurrently altered by single nucleotide variants (SN...
Identifying driver mutations and their functional consequences is critical to our understanding of c...
We have investigated the properties of three sets of human missense genetic variations: cancer somat...
<p>A) The number of mutations inside functional and control TFBSs, plotted for each tumour sample in...
Abstract Background Cancer mutations accumulate through replication errors and DNA damage coupled wi...
<p>The upper sequence chromatogram shows the heterozygous missense mutation in exon 14 in <i>FGFR2</...
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