Immunohistochemistry for Ki-67 in Hic-5+/+ and Hic-5-/- glomerulonephritis (GN) mice.

<p>(a) On day 7, Hic-5+/+ Habu GN mice showed a greater number of Ki-67-positive glomerular cells. In addition, more Ki-67-positive cells were observed in the glomeruli of Hic-5-/- Habu GN mice. There were few Ki-67-positive cells in the glomeruli of Hic-5+/+ and Hic-5-/- mice on day 0. Original magnification x200, scale bar = 50 μm. (b) The number of Ki-67-positive cells was counted in 30 glomeruli per section and calculated. The data are shown as the means ± SD. *, P<0.01. There was no significant difference between Hic-5+/+ day 0 and Hic-5-/- day 0.