Reduced PNA-positive glomeruli ratios in Neu5Ac-treated mt mice.

<p>(A) Kidneys double-stained for PC and PNA, from untreated ht (upper panels) and mt (middle panels) mice, and Neu5Ac-treated mt mice (bottom panels). Sections were stained with an anti-PC antibody (left panels; red), PNA (middle panels; green), and both (right panels; merge). Scale bars: 200 µm. (B) Ratio of PNA-positive to PC-positive glomeruli in the kidneys of 2-month-old untreated ht (green diamonds, n = 4) and mt (red triangles, n = 6) mice, and of Neu5Ac-treated ht (blue circles, n = 5) and mt (yellow squares, n = 8) mice. ***<i>P</i><0.001 (Two-way ANOVA).