<p>The first to third columns denote the effect sizes of SNP1, SNP2 and interaction in pure samples respectively. The fourth column of Table 1 indicates mixed proportion. The fifth and sixth columns of Table 1 indicates heritability and skewness respectively.</p><p>Models of simulation with Normal distribution.</p
Disease models for the two pairs of SNPs that contribute to the simulated outcome. Numeric values (e...
<p>(A) 20% associated SNPs for each phenotype and 75% extra overlaps between and and between and ...
<p>LME-RSI: a linear mixed-effects model with random slope and intercept; LME-RI: a linear mixed-eff...
Columns show parameters used for each version of the model. The weight of the second normal WB is va...
In the Dichotomous model (A), the density curve is replaced by a histogram, as effects sizes are str...
Scenario descriptions and parameter combinations are adapted directly from Ioannidis [1]. The remain...
<p>The true positive rate (TPR, row 1), false discovery rate (FDR, row 2) and false positive rate (F...
For simulation setting (3), shown are the RSSEs of the estimated joint probabilities to the true val...
<p>*. The simulation model consists of 5 covariates, each with OR of 1.5. In analysis, we assume tha...
Scenario descriptions and parameter combinations are adapted directly from Ioannidis [1]. The remain...
<p>The upper and lower figures show the results when the number of samples is equal to 1,000 and 3,0...
<p>Histograms of distributions of simulated respondents on the latent continuum used in this paper (...
<p>The first three columns are the averaged standard error observed from 100 simulations under three...
<p><i>δ</i> represents the impact value of the genotype at SNP location when there is no epistasis b...
<p>(A) Histogram of randomly-selected SNPs and highly-selected SNPs, both generated under a null mod...
Disease models for the two pairs of SNPs that contribute to the simulated outcome. Numeric values (e...
<p>(A) 20% associated SNPs for each phenotype and 75% extra overlaps between and and between and ...
<p>LME-RSI: a linear mixed-effects model with random slope and intercept; LME-RI: a linear mixed-eff...
Columns show parameters used for each version of the model. The weight of the second normal WB is va...
In the Dichotomous model (A), the density curve is replaced by a histogram, as effects sizes are str...
Scenario descriptions and parameter combinations are adapted directly from Ioannidis [1]. The remain...
<p>The true positive rate (TPR, row 1), false discovery rate (FDR, row 2) and false positive rate (F...
For simulation setting (3), shown are the RSSEs of the estimated joint probabilities to the true val...
<p>*. The simulation model consists of 5 covariates, each with OR of 1.5. In analysis, we assume tha...
Scenario descriptions and parameter combinations are adapted directly from Ioannidis [1]. The remain...
<p>The upper and lower figures show the results when the number of samples is equal to 1,000 and 3,0...
<p>Histograms of distributions of simulated respondents on the latent continuum used in this paper (...
<p>The first three columns are the averaged standard error observed from 100 simulations under three...
<p><i>δ</i> represents the impact value of the genotype at SNP location when there is no epistasis b...
<p>(A) Histogram of randomly-selected SNPs and highly-selected SNPs, both generated under a null mod...
Disease models for the two pairs of SNPs that contribute to the simulated outcome. Numeric values (e...
<p>(A) 20% associated SNPs for each phenotype and 75% extra overlaps between and and between and ...
<p>LME-RSI: a linear mixed-effects model with random slope and intercept; LME-RI: a linear mixed-eff...
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