<p>(A) 20% associated SNPs for each phenotype and 75% extra overlaps between and and between and ; (B) 20% associated SNPs and 25% extra overlaps; (C) 20% associated SNPs with varying extra overlaps (25% between and and 75% between and ); and (D) Varying proportion of associated SNPs (20% for and and 5% for and ) with 75% extra overlaps.</p
Quantitative traits are simulated to have broad-sense heritability of H2 = 0.2 with equal contributi...
<p>OR is tabulated for each genotype of causal SNPs as in Namkung <i>et al.</i><a href="http://www.p...
Quantitative traits are simulated to have broad-sense heritability of H2 = 0.6 with equal contributi...
The graphical scenario is presented for M = 10, 000 SNPs; K = 25 annotations; % of annotated SNPs in...
<p>The total number of studies is denoted by <i>K</i> and <i>m</i> denotes the minor allele frequenc...
<p>The total number of studies is denoted by <i>K</i> and <i>m</i> denotes the minor allele frequenc...
<p>The true positive rate (TPR, row 1), false discovery rate (FDR, row 2) and false positive rate (F...
a<p>denote the phenotypic variance explained by the additive genetic effects of SNP<sub>1</sub>, SNP...
a<p>denote the phenotypic variance explained by additive effects of causal SNP 6 and SNP 10 as well ...
<p>Estimations of the ratios of nonsynonymous to synonymous rates in the two genes ( and ) by simult...
<p>(A) QQ plot of -log10 p values from SNP set tests using different SNP weights under the null simu...
<p>Note: <sup>a</sup> denote the proportions of YRI individuals in cases-controls, respectively.</p>...
2000 simulated phenotypes for each species and the corresponding causal SNPs information
Disease models for the two pairs of SNPs that contribute to the simulated outcome. Numeric values (e...
Quantitative traits are simulated to have broad-sense heritability of H2 = 0.6 with equal contributi...
Quantitative traits are simulated to have broad-sense heritability of H2 = 0.2 with equal contributi...
<p>OR is tabulated for each genotype of causal SNPs as in Namkung <i>et al.</i><a href="http://www.p...
Quantitative traits are simulated to have broad-sense heritability of H2 = 0.6 with equal contributi...
The graphical scenario is presented for M = 10, 000 SNPs; K = 25 annotations; % of annotated SNPs in...
<p>The total number of studies is denoted by <i>K</i> and <i>m</i> denotes the minor allele frequenc...
<p>The total number of studies is denoted by <i>K</i> and <i>m</i> denotes the minor allele frequenc...
<p>The true positive rate (TPR, row 1), false discovery rate (FDR, row 2) and false positive rate (F...
a<p>denote the phenotypic variance explained by the additive genetic effects of SNP<sub>1</sub>, SNP...
a<p>denote the phenotypic variance explained by additive effects of causal SNP 6 and SNP 10 as well ...
<p>Estimations of the ratios of nonsynonymous to synonymous rates in the two genes ( and ) by simult...
<p>(A) QQ plot of -log10 p values from SNP set tests using different SNP weights under the null simu...
<p>Note: <sup>a</sup> denote the proportions of YRI individuals in cases-controls, respectively.</p>...
2000 simulated phenotypes for each species and the corresponding causal SNPs information
Disease models for the two pairs of SNPs that contribute to the simulated outcome. Numeric values (e...
Quantitative traits are simulated to have broad-sense heritability of H2 = 0.6 with equal contributi...
Quantitative traits are simulated to have broad-sense heritability of H2 = 0.2 with equal contributi...
<p>OR is tabulated for each genotype of causal SNPs as in Namkung <i>et al.</i><a href="http://www.p...
Quantitative traits are simulated to have broad-sense heritability of H2 = 0.6 with equal contributi...