Disease models for the two pairs of SNPs that contribute to the simulated outcome. Numeric values (e.g., 0.1, 0.2) are penetrance parameters for the corresponding genotype combinations. (MAF = 0.5 and 0.3, respectively for the two SNPs in each pair).</p
<p>The relative genotype risks are . <i>K</i> represents disease prevalence and <i>p</i> is the freq...
<p>Simulated parameters in all simulated experiments (3 alleles for marker and QTL, and 3 chromosome...
This dataset contains simulated genotypes and phenotypes from tetraploid organisms. 44 populations h...
Two SNP-pairs (where each wi, vj denotes the probability of the respective genotype combination) and...
<p>(A) 20% associated SNPs for each phenotype and 75% extra overlaps between and and between and ...
2000 simulated phenotypes for each species and the corresponding causal SNPs information
<p>Each entry in the tables represents the risk of the corresponding genotype combination relative t...
The penetrance tables for Trait I and Trait II are presented. Cell values indicate penetrance level,...
†<p>The disease prevalence is set at 0.1 and heritability is set a 0.02 for all simulations.</p>‡<p>...
<p>The true positive rate (TPR, row 1), false discovery rate (FDR, row 2) and false positive rate (F...
The graphical scenario is presented for M = 10, 000 SNPs; K = 25 annotations; % of annotated SNPs in...
Disease models without main effects, taken from [31], where they were specifically constructed in su...
<p><i>δ</i> represents the impact value of the genotype at SNP location when there is no epistasis b...
<p>(A) QQ plot of -log10 p values from SNP set tests using different SNP weights under the null simu...
<p>The relative genotype risks are . <i>K</i> represents disease prevalence and <i>p</i> is the freq...
<p>The relative genotype risks are . <i>K</i> represents disease prevalence and <i>p</i> is the freq...
<p>Simulated parameters in all simulated experiments (3 alleles for marker and QTL, and 3 chromosome...
This dataset contains simulated genotypes and phenotypes from tetraploid organisms. 44 populations h...
Two SNP-pairs (where each wi, vj denotes the probability of the respective genotype combination) and...
<p>(A) 20% associated SNPs for each phenotype and 75% extra overlaps between and and between and ...
2000 simulated phenotypes for each species and the corresponding causal SNPs information
<p>Each entry in the tables represents the risk of the corresponding genotype combination relative t...
The penetrance tables for Trait I and Trait II are presented. Cell values indicate penetrance level,...
†<p>The disease prevalence is set at 0.1 and heritability is set a 0.02 for all simulations.</p>‡<p>...
<p>The true positive rate (TPR, row 1), false discovery rate (FDR, row 2) and false positive rate (F...
The graphical scenario is presented for M = 10, 000 SNPs; K = 25 annotations; % of annotated SNPs in...
Disease models without main effects, taken from [31], where they were specifically constructed in su...
<p><i>δ</i> represents the impact value of the genotype at SNP location when there is no epistasis b...
<p>(A) QQ plot of -log10 p values from SNP set tests using different SNP weights under the null simu...
<p>The relative genotype risks are . <i>K</i> represents disease prevalence and <i>p</i> is the freq...
<p>The relative genotype risks are . <i>K</i> represents disease prevalence and <i>p</i> is the freq...
<p>Simulated parameters in all simulated experiments (3 alleles for marker and QTL, and 3 chromosome...
This dataset contains simulated genotypes and phenotypes from tetraploid organisms. 44 populations h...