<p>The first three columns are the averaged standard error observed from 100 simulations under three heritability levels. The last column is the predicted standard error from our approximation theory. The plotted data can be found in <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1004269#pgen.1004269.s002" target="_blank">Table S1</a>.</p
<p>The mean squared errors were obtained from 100 replicated simulations. The overall proportion of ...
<p>Average standardized transmission test over 1,000 replications for varying levels of genotype err...
<p>Relationship between GREML-based heritability estimates (Genetic Variance/Phenotypic Variance) an...
<p>The SE is predicted from the approximation theory given different levels of disease prevalence (<...
a<p>Estimate of variance explained by all SNPs with its standard error given in the parentheses. A f...
<p>Same sample: two traits are measured on the same set of samples. Different sample: two traits are...
<p>Variance component estimates (±standard errors) and heritabilities for simulation data with 3 dom...
<p>Variance component estimates (±standard errors) and heritabilities for simulation data with 200, ...
<p> indicates the number of SNP markers used in the model being evaluated. All other values indicate...
<p><i>N</i><sub>cases</sub>: number of cases. <i>N</i><sub>controls</sub>: number of controls. SE(Ob...
<p>For each effect size (1,2,3,4,5 or 10% of the total variance) 100 simulations were carried out. T...
<p>For each effect size (1,2,3,4,5 or 10% of the total variance) 100 simulations were carried out. T...
<p>The true positive rate (TPR, row 1), false discovery rate (FDR, row 2) and false positive rate (F...
<p>For each effect size (1,2,3,4,5 or 10% of the total variance) 100 simulations were carried out. T...
<p>The trait analyzed is first-visit SBP and DBP and long-term average (LTA) SBP and DBP respectivel...
<p>The mean squared errors were obtained from 100 replicated simulations. The overall proportion of ...
<p>Average standardized transmission test over 1,000 replications for varying levels of genotype err...
<p>Relationship between GREML-based heritability estimates (Genetic Variance/Phenotypic Variance) an...
<p>The SE is predicted from the approximation theory given different levels of disease prevalence (<...
a<p>Estimate of variance explained by all SNPs with its standard error given in the parentheses. A f...
<p>Same sample: two traits are measured on the same set of samples. Different sample: two traits are...
<p>Variance component estimates (±standard errors) and heritabilities for simulation data with 3 dom...
<p>Variance component estimates (±standard errors) and heritabilities for simulation data with 200, ...
<p> indicates the number of SNP markers used in the model being evaluated. All other values indicate...
<p><i>N</i><sub>cases</sub>: number of cases. <i>N</i><sub>controls</sub>: number of controls. SE(Ob...
<p>For each effect size (1,2,3,4,5 or 10% of the total variance) 100 simulations were carried out. T...
<p>For each effect size (1,2,3,4,5 or 10% of the total variance) 100 simulations were carried out. T...
<p>The true positive rate (TPR, row 1), false discovery rate (FDR, row 2) and false positive rate (F...
<p>For each effect size (1,2,3,4,5 or 10% of the total variance) 100 simulations were carried out. T...
<p>The trait analyzed is first-visit SBP and DBP and long-term average (LTA) SBP and DBP respectivel...
<p>The mean squared errors were obtained from 100 replicated simulations. The overall proportion of ...
<p>Average standardized transmission test over 1,000 replications for varying levels of genotype err...
<p>Relationship between GREML-based heritability estimates (Genetic Variance/Phenotypic Variance) an...