Comparative immunogenicity between mouse species.
- Gunnstein Norheim (798065)
- Holly Sanders (282547)
- Jardar W. Mellesdal (798066)
- Idunn Sundfør (798067)
- Hannah Chan (49338)
- Carina Brehony (798068)
- Caroline Vipond (798069)
- Chris Dold (798070)
- Rory Care (798071)
- Muhammad Saleem (97981)
- Martin C. J. Maiden (42431)
- Jeremy P. Derrick (136524)
- Ian Feavers (49339)
- Andrew J. Pollard (44971)
Publication date
September 2015
DOIAbstract
<p>Immunogenicity in three mouse species (NIH, Balb/c, C57/Black), analyzed by ELISA measuring total IgG and IgG2 against rFetA, rPorA, or whole cells (WC) of the vaccine strain 3207 (constitutive FetA expression and wt PorA expression). Two doses of OMVs (2.5ug protein/dose with Al(OH)3 adjuvant) were given to mice s.c. 3 weeks apart, and these were bled 3 weeks after the final dose. N.S.; not significantly different. *; significant difference detected.</p
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