<p>Serum bactericidal titres of sera (pools of four mice, five pools per group) were determined against four target strains using rabbit sera as the complement source. The table shows geometric mean titres, with the 95% confidence intervals of the mean in parentheses. Mice were given two doses of four dose levels or an adjuvant only control. Note that the data from mice given two doses of 2.5 μg protein per dose is included in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0140345#pone.0140345.t004" target="_blank">Table 4</a> for comparison, as the immunizations were performed concomitantly.</p><p>Immunogenicity (rSBA) of MenPF-1 vaccine in mice (dose levels 1.0–10.0 μg per dose).</p
<p>Groups of five BALB/c mice were immunized three times in three week intervals with 20 μg of rMUL2...
<p>Groups of 10 mice received 3 doses, 3 weeks apart of 2.5 μg CSP+SE, Qβ-CSP+SE, CSP+GLA/SE, Qβ-CSP...
<p>BALB/c mice (n = 15) were immunized with individual antigens (F1, F1B) and alum adjuvant. The ani...
<p>Serum bactericidal titres of sera (pools of four mice, five pools per group) were determined agai...
<p>Serum bactericidal titres of sera (pools of four mice, five pools per group) were determined agai...
<p>Serum bactericidal titres of sera (pools of four mice, five pools per group) were determined agai...
<p>Total IgG titres, calculated in comparison to a pooled standard serum, were determined for sera f...
<p>Total IgG titres calculated in comparison to a pooled standard serum, were determined for sera fr...
<p>(A) Female BALB/c mice were immunized with rSEB plus AlPO<sub>4</sub> adjuvant, AlPO<sub>4</sub> ...
<p>Immunogenicity in three mouse species (NIH, Balb/c, C57/Black), analyzed by ELISA measuring total...
<p>Serum neutralizing (neut) antibody and lung virus titers for each vaccine dosage group. A. Geomet...
<p>C57BL/6 mice were immunized 3x with 2.5 µg, 5 µg, or 20 µg of rCSP (CSP-1) formulated in differen...
<p>Per antigen, eight mice were vaccinated twice with 5 µg antigen mixed with an oil-in-water adjuva...
(A) Vaccination schedule to evaluate immunogenicity in male AKR/J mice. Humoral immune response was ...
<p>A) Groups of Balb/c mice (n = 9–10) were immunized with 1 µg of M2e peptide or M2e-NSP4 formulate...
<p>Groups of five BALB/c mice were immunized three times in three week intervals with 20 μg of rMUL2...
<p>Groups of 10 mice received 3 doses, 3 weeks apart of 2.5 μg CSP+SE, Qβ-CSP+SE, CSP+GLA/SE, Qβ-CSP...
<p>BALB/c mice (n = 15) were immunized with individual antigens (F1, F1B) and alum adjuvant. The ani...
<p>Serum bactericidal titres of sera (pools of four mice, five pools per group) were determined agai...
<p>Serum bactericidal titres of sera (pools of four mice, five pools per group) were determined agai...
<p>Serum bactericidal titres of sera (pools of four mice, five pools per group) were determined agai...
<p>Total IgG titres, calculated in comparison to a pooled standard serum, were determined for sera f...
<p>Total IgG titres calculated in comparison to a pooled standard serum, were determined for sera fr...
<p>(A) Female BALB/c mice were immunized with rSEB plus AlPO<sub>4</sub> adjuvant, AlPO<sub>4</sub> ...
<p>Immunogenicity in three mouse species (NIH, Balb/c, C57/Black), analyzed by ELISA measuring total...
<p>Serum neutralizing (neut) antibody and lung virus titers for each vaccine dosage group. A. Geomet...
<p>C57BL/6 mice were immunized 3x with 2.5 µg, 5 µg, or 20 µg of rCSP (CSP-1) formulated in differen...
<p>Per antigen, eight mice were vaccinated twice with 5 µg antigen mixed with an oil-in-water adjuva...
(A) Vaccination schedule to evaluate immunogenicity in male AKR/J mice. Humoral immune response was ...
<p>A) Groups of Balb/c mice (n = 9–10) were immunized with 1 µg of M2e peptide or M2e-NSP4 formulate...
<p>Groups of five BALB/c mice were immunized three times in three week intervals with 20 μg of rMUL2...
<p>Groups of 10 mice received 3 doses, 3 weeks apart of 2.5 μg CSP+SE, Qβ-CSP+SE, CSP+GLA/SE, Qβ-CSP...
<p>BALB/c mice (n = 15) were immunized with individual antigens (F1, F1B) and alum adjuvant. The ani...