<p>Serum bactericidal titres of sera (pools of four mice, five pools per group) were determined against four target strains using rabbit sera as the complement source. The table shows geometric mean titres, with the 95% confidence intervals of the mean in parentheses. Mice were given 1, 2, 3 or 4 doses of 2.5 μg protein per dose. Note that the data from mice given two doses of 2.5 μg protein per dose is included in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0140345#pone.0140345.t002" target="_blank">Table 2</a> for comparison, as the immunizations were performed concomitantly.</p><p>Immunogenicity (rSBA) of MenPF-1 vaccine in mice (number of doses).</p
<p>Five C57BL/6 mice per cohort were immunized 3x with 25 µg of rCSP from 3 production strains (CSP-...
<p>BALB/c mice (n = 15) were immunized with individual antigens (F1, F1B) and alum adjuvant. The ani...
Groups of 10 Balb/c mice were immunized with Flg-HA2-2-4M2e, Flg-HA2-1-4M2e, or Flg-4M2e fusion prot...
<p>Serum bactericidal titres of sera (pools of four mice, five pools per group) were determined agai...
<p>Serum bactericidal titres of sera (pools of four mice, five pools per group) were determined agai...
<p>Serum bactericidal titres of sera (pools of four mice, five pools per group) were determined agai...
<p>Total IgG titres, calculated in comparison to a pooled standard serum, were determined for sera f...
<p>Total IgG titres calculated in comparison to a pooled standard serum, were determined for sera fr...
<p>Immunogenicity in three mouse species (NIH, Balb/c, C57/Black), analyzed by ELISA measuring total...
(A) Vaccination schedule to evaluate immunogenicity in male AKR/J mice. Humoral immune response was ...
<p>(A) Female BALB/c mice were immunized with rSEB plus AlPO<sub>4</sub> adjuvant, AlPO<sub>4</sub> ...
<p>A) Groups of Balb/c mice (n = 9–10) were immunized with 1 µg of M2e peptide or M2e-NSP4 formulate...
<p>Per antigen, eight mice were vaccinated twice with 5 µg antigen mixed with an oil-in-water adjuva...
<p>Groups of 10 mice received 3 doses, 3 weeks apart of 2.5 μg CSP+SE, Qβ-CSP+SE, CSP+GLA/SE, Qβ-CSP...
<p>Experimental groups of mice used in the immunogenicity and protective potential trials of Protein...
<p>Five C57BL/6 mice per cohort were immunized 3x with 25 µg of rCSP from 3 production strains (CSP-...
<p>BALB/c mice (n = 15) were immunized with individual antigens (F1, F1B) and alum adjuvant. The ani...
Groups of 10 Balb/c mice were immunized with Flg-HA2-2-4M2e, Flg-HA2-1-4M2e, or Flg-4M2e fusion prot...
<p>Serum bactericidal titres of sera (pools of four mice, five pools per group) were determined agai...
<p>Serum bactericidal titres of sera (pools of four mice, five pools per group) were determined agai...
<p>Serum bactericidal titres of sera (pools of four mice, five pools per group) were determined agai...
<p>Total IgG titres, calculated in comparison to a pooled standard serum, were determined for sera f...
<p>Total IgG titres calculated in comparison to a pooled standard serum, were determined for sera fr...
<p>Immunogenicity in three mouse species (NIH, Balb/c, C57/Black), analyzed by ELISA measuring total...
(A) Vaccination schedule to evaluate immunogenicity in male AKR/J mice. Humoral immune response was ...
<p>(A) Female BALB/c mice were immunized with rSEB plus AlPO<sub>4</sub> adjuvant, AlPO<sub>4</sub> ...
<p>A) Groups of Balb/c mice (n = 9–10) were immunized with 1 µg of M2e peptide or M2e-NSP4 formulate...
<p>Per antigen, eight mice were vaccinated twice with 5 µg antigen mixed with an oil-in-water adjuva...
<p>Groups of 10 mice received 3 doses, 3 weeks apart of 2.5 μg CSP+SE, Qβ-CSP+SE, CSP+GLA/SE, Qβ-CSP...
<p>Experimental groups of mice used in the immunogenicity and protective potential trials of Protein...
<p>Five C57BL/6 mice per cohort were immunized 3x with 25 µg of rCSP from 3 production strains (CSP-...
<p>BALB/c mice (n = 15) were immunized with individual antigens (F1, F1B) and alum adjuvant. The ani...
Groups of 10 Balb/c mice were immunized with Flg-HA2-2-4M2e, Flg-HA2-1-4M2e, or Flg-4M2e fusion prot...