Injury induces stronger keratinocyte proliferation and more angiogenesis in IL-4 Tg mice than in WT mice.

<p>Three mm full thickness excisional wounds were made on dorsal skin of IL-4 Tg and WT mice. a) Percent of Ki67 positive keratinocytes. b, c, and d) EGF, IGF-1, and FGF-7 (KGF-1) mRNA expression, respectively. e) Vessel density expressed as the percent CD31 positive area in wounds. f) VEGF mRNA expression. * p<0.05 and ^# p<0.01 compared to the other group at the same time point, respectively. NS: normal or unwounded skin. The number of mice used at each time point was 5.