Wounds from NLRP-3 KO and caspase-1 KO mice exhibit impaired angiogenesis.

<p>Wound sections were stained with antibodies against CD31. (A) Representative images of CD31 stained sections, scale bar = 0.5 mm. (B-C) CD31 staining was quantified using the percentage of wound bed area stained. (D-E) In addition, levels of the pro-angiogenic growth factors VEGF and (F) FGF-2 were measured using ELISA in wound homogenates. Data presented as mean ± SE, <i>n</i> = 5–8 wounds per group. *<i>P≤</i> 0.05.