Analysis of cardiolipin species in DU145 cells following SCD inhibition. (a) DU145 cells were cultured for 48hrs in medium containing full (FS) or low (LS) serum. Amounts of different cardiolipin (CL) species were detected by LC-MS/MS. (b) DU145 cells were treated with SCD inhibitors (100nM) or solvent (DMSO) for 48hrs in medium containing low serum. Amounts of different cardiolipin (CL) species are shown. Data represent the mean ÂąSEM of three biologically independent replicates. Statistical comparisons were performed using Student t-test (*pâ¤0.05). (PDF 443 kb
Figure S1. GC/MS quantification of 8-HOA from Nc-si, D5D-KD and D5D/COX-2 double-KD MDA-MB 231/4 T1 ...
Table S1. Statistical analysis (ANOVA) for tumor size in Fig. 4a. The four groups are: Group 1: D5D-...
Figure S12. Proteasome inhibitors combined with fatty acid inhibition induce synergistic cell death....
Analysis of phosphatidylethanolamine species in DU145 cells following SCD inhibition. DU145 cells we...
The changes of CL and MLCL species with AA supplementation in RAW 264.7 cell without KLA. CL (A) and...
The changes of CL and MLCL species with EPA supplementation in RAW 264.7 cell without KLA. In panel ...
The changes of CL and MLCL species with DHA supplementation in RAW 264.7 cell without KLA. In panel ...
Table S1. The real time PCR primers. Table S2. The content of fatty acids in the cells. (DOCX 22 kb
Figure S1. SCD1 promotes migration and invasion of SW116 cells. (A) Quantification results of SCD1 i...
NAMPT inhibitor FK866 depletes NAD+ levels and impairs proliferation. (a, b, d, e, g, h) Intracellul...
Table S2. Statistical analysis (ANOVA) for tumor size in Fig. 4b. The four groups are: Group 5: D5D-...
Effect of FABP7 overexpression on the 786-O cell line. 786-O cells were cultured for two days in RPM...
Figure S1. D5D-KD alone did not affect HCA-7 cell growth. A. Colony formation of D5D-WT and D5D-KD H...
Proliferation of TUHR14TKB cells transfected with an FABP7 expression vector. The proliferation of c...
Additional file 2: Figure S2. Cholesterol depletion induced cell death in various cell lines. [a] ch...
Figure S1. GC/MS quantification of 8-HOA from Nc-si, D5D-KD and D5D/COX-2 double-KD MDA-MB 231/4 T1 ...
Table S1. Statistical analysis (ANOVA) for tumor size in Fig. 4a. The four groups are: Group 1: D5D-...
Figure S12. Proteasome inhibitors combined with fatty acid inhibition induce synergistic cell death....
Analysis of phosphatidylethanolamine species in DU145 cells following SCD inhibition. DU145 cells we...
The changes of CL and MLCL species with AA supplementation in RAW 264.7 cell without KLA. CL (A) and...
The changes of CL and MLCL species with EPA supplementation in RAW 264.7 cell without KLA. In panel ...
The changes of CL and MLCL species with DHA supplementation in RAW 264.7 cell without KLA. In panel ...
Table S1. The real time PCR primers. Table S2. The content of fatty acids in the cells. (DOCX 22 kb
Figure S1. SCD1 promotes migration and invasion of SW116 cells. (A) Quantification results of SCD1 i...
NAMPT inhibitor FK866 depletes NAD+ levels and impairs proliferation. (a, b, d, e, g, h) Intracellul...
Table S2. Statistical analysis (ANOVA) for tumor size in Fig. 4b. The four groups are: Group 5: D5D-...
Effect of FABP7 overexpression on the 786-O cell line. 786-O cells were cultured for two days in RPM...
Figure S1. D5D-KD alone did not affect HCA-7 cell growth. A. Colony formation of D5D-WT and D5D-KD H...
Proliferation of TUHR14TKB cells transfected with an FABP7 expression vector. The proliferation of c...
Additional file 2: Figure S2. Cholesterol depletion induced cell death in various cell lines. [a] ch...
Figure S1. GC/MS quantification of 8-HOA from Nc-si, D5D-KD and D5D/COX-2 double-KD MDA-MB 231/4 T1 ...
Table S1. Statistical analysis (ANOVA) for tumor size in Fig. 4a. The four groups are: Group 1: D5D-...
Figure S12. Proteasome inhibitors combined with fatty acid inhibition induce synergistic cell death....