Steady states of CHO-K1.

<p><b>(a)</b> Growth rate in steady states as a function of <i>ξ</i>. <b>(b)</b> Bifurcation diagram of cell density versus growth rate. A bistable regime emerges as a consequence of toxic byproduct accumulation. The hysteresis loop is highlighted with orange arrows. The metabolic transitions depicted in <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1005835#pcbi.1005835.g007" target="_blank">Fig 7</a> are depicted with red lines (in (a)) and red dots (in (b)).