<p>Groups of monkeys (n = 30/group) were intoxicated with 1.7x LD<sub>50</sub>/kg dose of BoNT/A and monitored hourly for the onset of clinical signs. Monkeys were individually administered with either BAT at 1x scaled human dose or placebo intravenously after the onset of clinical signs indicative of botulism (Study 2) and monitored for survival to 21 days post-toxin exposure.</p
<p>A 10 LD<sub>50</sub> dose of toxin was administered by intraperitoneal injection either 1.5 or 3 ...
Zoo animals, including tigers, have been reported to suffer from barbiturate intoxication, with pent...
<p>Groups of animals (n = 3) were exposed to 10 fold reductions in viral titer in six different expe...
<p>Estimated median time to onset of clinical signs for monkeys intoxicated with 1.7xLD<sub>50</sub>...
<p>A 10 LD<sub>50</sub> dose of BoNT/A1 was administered by intraperitoneal injection to groups of f...
Survival data for each of four BAT dose dilutions and placebo control is plotted against time for ea...
<p>Monkeys confirmed to have second stage HAT were administered DB868 orally, beginning at 28 days p...
<p>Starting at 7 days post-infection with <i>T. b. rhodesiense</i> KETRI 2537, monkeys confirmed to ...
<p>The monkeys confirmed to have first stage HAT were administered DB868 orally, beginning at 7 days...
<p>Groups of five mice (80 mice in total) were treated with 3×10<sup>10</sup> vp of Ad/VNA-BoNTA or ...
<p>Monkeys confirmed to have second stage HAT were administered DB829 intramuscularly, beginning at ...
<p>Protection of mice from BoNT/B lethality by administration of a double-tagged heterodimer of anti...
<p>Groups of five mice (60 mice in total) were treated and challenged as for study 1 (<a href="http:...
<p>Monkeys were infected with <i>T. b. rhodesiense</i> KETRI 2537 and upon confirmation of onset of ...
<p>Symptoms of intoxication and time to death were monitored following administration of the indicat...
<p>A 10 LD<sub>50</sub> dose of toxin was administered by intraperitoneal injection either 1.5 or 3 ...
Zoo animals, including tigers, have been reported to suffer from barbiturate intoxication, with pent...
<p>Groups of animals (n = 3) were exposed to 10 fold reductions in viral titer in six different expe...
<p>Estimated median time to onset of clinical signs for monkeys intoxicated with 1.7xLD<sub>50</sub>...
<p>A 10 LD<sub>50</sub> dose of BoNT/A1 was administered by intraperitoneal injection to groups of f...
Survival data for each of four BAT dose dilutions and placebo control is plotted against time for ea...
<p>Monkeys confirmed to have second stage HAT were administered DB868 orally, beginning at 28 days p...
<p>Starting at 7 days post-infection with <i>T. b. rhodesiense</i> KETRI 2537, monkeys confirmed to ...
<p>The monkeys confirmed to have first stage HAT were administered DB868 orally, beginning at 7 days...
<p>Groups of five mice (80 mice in total) were treated with 3×10<sup>10</sup> vp of Ad/VNA-BoNTA or ...
<p>Monkeys confirmed to have second stage HAT were administered DB829 intramuscularly, beginning at ...
<p>Protection of mice from BoNT/B lethality by administration of a double-tagged heterodimer of anti...
<p>Groups of five mice (60 mice in total) were treated and challenged as for study 1 (<a href="http:...
<p>Monkeys were infected with <i>T. b. rhodesiense</i> KETRI 2537 and upon confirmation of onset of ...
<p>Symptoms of intoxication and time to death were monitored following administration of the indicat...
<p>A 10 LD<sub>50</sub> dose of toxin was administered by intraperitoneal injection either 1.5 or 3 ...
Zoo animals, including tigers, have been reported to suffer from barbiturate intoxication, with pent...
<p>Groups of animals (n = 3) were exposed to 10 fold reductions in viral titer in six different expe...