Diminished cytokine production in Ly6C⁺ naïve CD8 T cells, compared to Sham-derived Ly6C⁺ naïve CD8 T cells.

(A) gMFI of IFNγ in Ly6C+ naïve CD8 T cells derived from mice 28 days post-sham or CLP surgery after ex vivo 5-hour stimulation with IL-12/IL-18/IL-2. (B) IFNγ, TNFα, and IL-2 gMFI of Ly6C+ naïve CD8 T cells from mice 28 days post-sham or CLP surgery after ex vivo 5-hour stimulation with PMA/Iono. Data are representative from at least three independent experiments with at least 5 mice per group. Error bars represent SEM. Numbers indicate p values. (EPS)