Depression - the first symptom of a brain tumor or a consequence of the process neoplastic process - a review of the literature

ANTKOWIAK, Klaudia, CIECIERSKI-KOŹLAREK , Hubert, ŻUREK, Urszula, TOŁWIŃSKI, Ignacy, KĘDZIERSKA, Zofia, DADAS, Klaudia, ŚWIERCZ, Aleksandra, MAŁACHOWSKA, Dominika and SHVED, Kateryna. Depression - the first symptom of a brain tumor or a consequence of the process neoplastic process - a review of the literature. Journal of Education, Health and Sport. 2023;46(1):233-246. eISSN 2391-8306. https://dx.doi.org/10.12775/JEHS.2023.46.01.016 https://apcz.umk.pl/JEHS/article/view/45338 https://zenodo.org/record/8284926 The journal has had 40 points in Ministry of Education and Science of Poland parametric evaluation. Annex to the announcement of the Minister of Education and Science of 17.07.2023 No. 32318. Has a Journal's Unique Identifier: 201159. Scientific disciplines assigned: Physical Culture Sciences (Field of Medical sciences and health sciences); Health Sciences (Field of Medical Sciences and Health Sciences). Punkty Ministerialne z 2019 - aktualny rok 40 punktów. Załącznik do komunikatu Ministra Edukacji i Nauki z dnia 17.07.2023 Lp. 32318. Posiada Unikatowy Identyfikator Czasopisma: 201159. Przypisane dyscypliny naukowe: Nauki o kulturze fizycznej (Dziedzina nauk medycznych i nauk o zdrowiu); Nauki o zdrowiu (Dziedzina nauk medycznych i nauk o zdrowiu). © The Authors 2023; This article is published with open access at Licensee Open Journal Systems of Nicolaus Copernicus University in Torun, Poland Open Access. This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author (s) and source are credited. This is an open access article licensed under the terms of the Creative Commons Attribution Non commercial license Share alike. (http://creativecommons.org/licenses/by-nc-sa/4.0/) which permits unrestricted, non commercial use, distribution and reproduction in any medium, provided the work is properly cited. The authors declare that there is no conflict of interests regarding the publication of this paper. Received: 25.07.2023. Revised:21.08.2023. Accepted: 25.08.2023. Published: 29.08.2023. Depression- the first symptom of a brain tumor or a consequence of the process neoplastic process - a review of the literature Klaudia Antkowiak Szpital Średzki Serca Jezusowego z.o.o ul. Żwirki i Wigury 10, 63-000 Środa Wielkopolska, Poland ORCiD: 0009-0008-3421-2200 e-mail: klaudia.antkowiak2021@gmail.com Hubert Ciecierski-Koźlarek Wojewódzki Szpital Specjalistyczny w Olsztynie, ul. Żołnierska 18, 10-561 Olsztyn, Poland ORCiD: 0009-0009-4062-6888 e-mail: hubertciecierski@icloud.com Urszula Żurek Warszawski Szpital Południowy, ul. rtm. Witolda Pileckiego 99, 02-781 Warszawa, Poland ORCiD: 0009-0008-3482-5381 e-mail: ula.zurek@gmail.com Ignacy Tołwiński Warszawski Szpital Południowy, ul. rtm. Witolda Pileckiego 99, 02-781 Warszawa, Poland ORCiD: 0000-0003-1362-6734 e-mail: ignacyt233@gmail.com Zofia Kędzierska Warszawski Szpital Południowy, ul. rtm. Witolda Pileckiego 99, 02-781 Warszawa, Poland ORCiD: 0000-0002-4181-4719 e-mail: zo.kedzierska@gmail.com 124 Klaudia Dadas Warszawski Szpital Południowy, ul. rtm. Witolda Pileckiego 99, 02-781 Warszawa, Poland ORCiD: 0009-0007-3352-9807 e-mail: klaudia.w.2703@gmail.com Aleksandra Świercz Warszawski Szpital Południowy, ul. rtm. Witolda Pileckiego 99, 02-781 Warszawa, Poland ORCiD: 0009-0007-1535-1590 e-mail: aleksandra.swiercz1996@gmail.com Dominika Małachowska Warszawski Szpital Południowy, ul. rtm. Witolda Pileckiego 99, 02-781 Warszawa, Poland ORCiD: 0009-0008-6305-7959 e-mail: dominika1.malachowska@gmail.com Kateryna Shved Wielospecjalistyczny Szpital Miejski im. Józefa Strusia, ul. Szwajcarska 3, 61-285 Poznań, Poland ORCiD: 0009-0002-3773-7025 e-mail: katey.shved@gmail.com Abstract: Introduction and objective CNS malignancies account for about 1.6% of all diseases today. In people diagnosed with a brain tumor with a poor prognosis, we often see disorders from the psychiatric spectrum, most often depressive disorders. In this paper, we want to focus on whether depression occurs as a sequel to cancer or perhaps is the first of the symptoms of a CNS tumor. Review methods For the analysis, the PubMed medical database was searched, and articles containing studies and case reports of people with CNS tumor and depressive disorders that occurred either before diagnosis or at any time during the course of the disease were selected Abbreviated description of the state of knowledge CNS tumors produce symptoms such as epilepsy, visual disturbances, paresis, but also behavioral disorders. This is determined by the location of the tumor. Depression is a mental disorder manifested mainly by lowered mood. This disorder can coexist with tumors occurring in the frontal lobe or be present regardless of the location of the tumor, in people diagnosed with a tumor with a poor prognosis. Summary Analyzing the selected articles, we see that in people who were diagnosed with a tumor located in the frontal lobe, often the first symptom was depressive disorders, which even preceded neurological symptoms. When depression is diagnosed, appearing suddenly and refractory to treatment, one should consider whether there is an underlying pathological lesion in the CNS. Unfortunately, there are no specific guidelines for imaging studies in depressive disorders. People who suffer from malignant tumors with a poor prognosis should be cared for by a psychologist, because as the disease progresses, the symptoms worsen, affecting the prognosis. Keywords: brain tumor; glioblastoma multiforme; depression; cognitive impairment; cancer