Very high diastereoselectivity can be achieved by 1,3-chelation-controlled allylation of aldehydes that possess a non-chelating -ether substituent, even if the -position is a quaternary centre and/or a spiro-epoxide. This reaction was used as a key step in an enantioselective synthesis of the angiogenesis inhibitor luminacinD.Very high diastereoselectivity can be achieved by 1,3-chelation-controlled allylation of aldehydes that possess a non-chelating -ether substituent, even if the -position is a quaternary centre and/or a spiro-epoxide. This reaction was used as a key step in an enantioselective synthesis of the angiogenesis inhibitor luminacinD.A
The authors would like to acknowledge EPSRC for PhD funding through the Doctoral Training Schemes.Th...
The ability of the catalytic, asymmetric acyl halide-aldehyde cyclocondensation (AAC) reaction to pr...
The development of catalytic, enantioselective methods for the construction of quaternary stereogeni...
Very high diastereoselectivity can be achieved by 1,3-chelation-controlled allylation of aldehydes t...
Very high diastereoselectivity can be achieved by 1,3-chelation-controlled allylation of aldehydes t...
A proposed strategy for the enantioselective total synthesis of luminacin D, one of a family of 14 s...
A second generation synthesis of (?)-luminacin D based on an early stage introduction of the trisubs...
[GRAPHICS]A series of structurally simplified luminacin analogues devoid of the epoxide ring are ass...
The efficient synthesis of all-C quaternary centres as part of an acyclic contiguous stereoarray is ...
Luminacin D belongs to a family of bioactive compounds isolated from the fermentation broth of soil ...
Stereochemical alchemy! Racemic allyl β-ketoesters allow the regiocontrolled formation of enolates, ...
A second-generation synthesis of (-)-luminacin D based on an early stage introduction of the trisubs...
A second-generation synthesis of (−)-luminacin D based on an early stage introduction of the trisubs...
A new asymmetric synthetic route to (-)-galanthamine (1.01), a potent Amaryllidaceae alkaloid used i...
The synthesis of complex molecules is one of the most challenging goals for synthetic chemists. The ...
The authors would like to acknowledge EPSRC for PhD funding through the Doctoral Training Schemes.Th...
The ability of the catalytic, asymmetric acyl halide-aldehyde cyclocondensation (AAC) reaction to pr...
The development of catalytic, enantioselective methods for the construction of quaternary stereogeni...
Very high diastereoselectivity can be achieved by 1,3-chelation-controlled allylation of aldehydes t...
Very high diastereoselectivity can be achieved by 1,3-chelation-controlled allylation of aldehydes t...
A proposed strategy for the enantioselective total synthesis of luminacin D, one of a family of 14 s...
A second generation synthesis of (?)-luminacin D based on an early stage introduction of the trisubs...
[GRAPHICS]A series of structurally simplified luminacin analogues devoid of the epoxide ring are ass...
The efficient synthesis of all-C quaternary centres as part of an acyclic contiguous stereoarray is ...
Luminacin D belongs to a family of bioactive compounds isolated from the fermentation broth of soil ...
Stereochemical alchemy! Racemic allyl β-ketoesters allow the regiocontrolled formation of enolates, ...
A second-generation synthesis of (-)-luminacin D based on an early stage introduction of the trisubs...
A second-generation synthesis of (−)-luminacin D based on an early stage introduction of the trisubs...
A new asymmetric synthetic route to (-)-galanthamine (1.01), a potent Amaryllidaceae alkaloid used i...
The synthesis of complex molecules is one of the most challenging goals for synthetic chemists. The ...
The authors would like to acknowledge EPSRC for PhD funding through the Doctoral Training Schemes.Th...
The ability of the catalytic, asymmetric acyl halide-aldehyde cyclocondensation (AAC) reaction to pr...
The development of catalytic, enantioselective methods for the construction of quaternary stereogeni...
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