A second-generation synthesis of (-)-luminacin D based on an early stage introduction of the trisubstituted epoxide group is reported, allowing access to the natural product in an improved yield and a reduced number of steps (5.4%, 17 steps vs 2.6%, 19 steps). A full account of the optimization work is provided, with the reversal of stereoselection in the formation of the C4 alcohol in equally excellent diastereoselectivity as the key improvement
International audienceThis account describes an efficient and modulable total synthesis of (+)-disco...
This account describes our efforts toward developing a stereodivergent entry to perophoramidine and ...
D.Phil.The objective of the research described in the first part of this thesis was to develop a gen...
A second-generation synthesis of (−)-luminacin D based on an early stage introduction of the trisubs...
A second generation synthesis of (?)-luminacin D based on an early stage introduction of the trisubs...
A 15-step synthesis of (+/-)-luminacin D from ethyl pent-2-ynoate is reported. The pivotal step invo...
[GRAPHICS]A series of structurally simplified luminacin analogues devoid of the epoxide ring are ass...
A proposed strategy for the enantioselective total synthesis of luminacin D, one of a family of 14 s...
Very high diastereoselectivity can be achieved by 1,3-chelation-controlled allylation of aldehydes t...
Very high diastereoselectivity can be achieved by 1,3-chelation-controlled allylation of aldehydes t...
Luminacin D belongs to a family of bioactive compounds isolated from the fermentation broth of soil ...
A new synthetic route for the total synthesis of dendrodolide-L has been developed from known chiral...
The stereoselective synthesis of resolvin D4 (RvD4) was achieved using the Wittig reaction of the C1...
This article describes the first total synthesis of luminamicin using a strategy combining chemical ...
The total synthesis of maremycins A, B, C-1/C-2, D-1, and D-2 is achieved starting from the natural ...
International audienceThis account describes an efficient and modulable total synthesis of (+)-disco...
This account describes our efforts toward developing a stereodivergent entry to perophoramidine and ...
D.Phil.The objective of the research described in the first part of this thesis was to develop a gen...
A second-generation synthesis of (−)-luminacin D based on an early stage introduction of the trisubs...
A second generation synthesis of (?)-luminacin D based on an early stage introduction of the trisubs...
A 15-step synthesis of (+/-)-luminacin D from ethyl pent-2-ynoate is reported. The pivotal step invo...
[GRAPHICS]A series of structurally simplified luminacin analogues devoid of the epoxide ring are ass...
A proposed strategy for the enantioselective total synthesis of luminacin D, one of a family of 14 s...
Very high diastereoselectivity can be achieved by 1,3-chelation-controlled allylation of aldehydes t...
Very high diastereoselectivity can be achieved by 1,3-chelation-controlled allylation of aldehydes t...
Luminacin D belongs to a family of bioactive compounds isolated from the fermentation broth of soil ...
A new synthetic route for the total synthesis of dendrodolide-L has been developed from known chiral...
The stereoselective synthesis of resolvin D4 (RvD4) was achieved using the Wittig reaction of the C1...
This article describes the first total synthesis of luminamicin using a strategy combining chemical ...
The total synthesis of maremycins A, B, C-1/C-2, D-1, and D-2 is achieved starting from the natural ...
International audienceThis account describes an efficient and modulable total synthesis of (+)-disco...
This account describes our efforts toward developing a stereodivergent entry to perophoramidine and ...
D.Phil.The objective of the research described in the first part of this thesis was to develop a gen...