Resulting <i>p</i>-values for cross-scoring 23 drug classes GWAS against very severe COVID-19 GWAS for anti-coherence (A) and coherence (B).

Each data point corresponds to a gene. The dotted red line marks a Bonferroni significance threshold of 1.18×10−7 (0.05 divided by the 18453 genes tested and 23 drug classes). Note that the drug class M05B shows the most significant enrichment in coherence with severe COVID-19.