Resulting <i>p</i>-values for cross-scoring several GWAS related to osteoporosis against the severe COVID-19 GWAS.

The top figure (A) shows the anti-coherent case and the bottom figure (B) the coherent case. The red dotted line marks the Bonferroni significance threshold of 3.9 × 10−7 (0.05 divided by the 18453 genes tested and 7 traits). We observe Bonferroni significant enrichment for RA plus enrichments in vitamin D and calcium with p-values −5.