Solid and dashed lines correspond to the stable and unstable steady states. The solid circle marks saddle-nodes (SN1~4). (TIF)</p
2 pages, 1 figureMotivation Multi-steady state behaviour, and in particular multi-stability, provid...
Motivation: Regulatory gene networks contain generic modules such as feedback loops that are essenti...
<p>(A) The topology of Network 1 was also predicted to have high probability for multistability. Net...
Solid and dashed lines correspond to the stable and unstable steady states. The solid circle marks s...
Solid and dashed correspond to stable and unstable steady states. The solid circles denote the saddl...
<p>The maximum and minimum numbers of protein R are plotted as a function of the R protein degradati...
<p>(A) The topology of Network 1 is used to mimic iPSC experiments with added constitutive expressio...
<p>(A) Bifurcation diagram of the system in Equation 1, an idealized model of a gene activated by si...
<p>The dependence of the steady states of variable <i>R</i><sub>c</sub> (RNA level of c-KIT) on para...
<p>The dependence of the steady states of variable <i>R</i><sub>c</sub> (RNA level of c-KIT) on para...
<p>(A) Wip1 synthesis rate <i>s</i><sub>1</sub> = 0.2, (B) <i>s</i><sub>1</sub> = 0.4. The stable an...
<p>(A) Complete bifurcation diagram. Inset: detail of branches near . (B) Amplification of states re...
<p>The thick lines are stable steady states, the dashed lines are unstable steady states. (A). A loa...
<p>Scheme showing a possible bifurcation diagram for the systems <a href="http://www.plosone.org/art...
(A) Parameter condition for the existence of local maximum and minimum for degradation plus dilution...
2 pages, 1 figureMotivation Multi-steady state behaviour, and in particular multi-stability, provid...
Motivation: Regulatory gene networks contain generic modules such as feedback loops that are essenti...
<p>(A) The topology of Network 1 was also predicted to have high probability for multistability. Net...
Solid and dashed lines correspond to the stable and unstable steady states. The solid circle marks s...
Solid and dashed correspond to stable and unstable steady states. The solid circles denote the saddl...
<p>The maximum and minimum numbers of protein R are plotted as a function of the R protein degradati...
<p>(A) The topology of Network 1 is used to mimic iPSC experiments with added constitutive expressio...
<p>(A) Bifurcation diagram of the system in Equation 1, an idealized model of a gene activated by si...
<p>The dependence of the steady states of variable <i>R</i><sub>c</sub> (RNA level of c-KIT) on para...
<p>The dependence of the steady states of variable <i>R</i><sub>c</sub> (RNA level of c-KIT) on para...
<p>(A) Wip1 synthesis rate <i>s</i><sub>1</sub> = 0.2, (B) <i>s</i><sub>1</sub> = 0.4. The stable an...
<p>(A) Complete bifurcation diagram. Inset: detail of branches near . (B) Amplification of states re...
<p>The thick lines are stable steady states, the dashed lines are unstable steady states. (A). A loa...
<p>Scheme showing a possible bifurcation diagram for the systems <a href="http://www.plosone.org/art...
(A) Parameter condition for the existence of local maximum and minimum for degradation plus dilution...
2 pages, 1 figureMotivation Multi-steady state behaviour, and in particular multi-stability, provid...
Motivation: Regulatory gene networks contain generic modules such as feedback loops that are essenti...
<p>(A) The topology of Network 1 was also predicted to have high probability for multistability. Net...
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