Additional file 1 of Evaluation of the added value of viral genomic information for predicting severity of influenza infection

Additional file 1. Appendix A: Internal validation. Appendix B: Exploration of other data analysis scenarios. Appendix C: Comparison baseline characteristics to assess selection bias. Appendix D: List of 25 mutations with an unadjusted p-value below 0.05. Appendix E: Manhattan plot. Appendix F: Principle Component Analysis (PCA). Appendix G: Apparent Area Under the ROC curve. Appendix H: Boxplots of the fitted values for the host and the combined model. Appendix I: Genomic model