Pre- and post-vaccination SHM rates in selected IGHV segments according to vaccination trial. Dots depict mutation rate in VH region (%) per lineage. A total of 670 randomly sampled lineages per individual were selected, filtered according IGHV use, and plotted. (Kruskal-Wallis test. Dunn’s correction for multiple testing. **P <0.01, ***P <0.001). (PDF 565 kb
Effect of B. longum + Gl-OS on levels of vaccine-specific IgA, IgG1, IgD and IgM. Data are optical d...
Reads, clonal groups, and lineages numbers per individual and condition. The table shows the number ...
Figure S6. NGS data on IgG4+ BCR clones. NGS data portraying the frequency of IgG4+ BCR clones (red)...
Per individual effect of immunization with 09 MIV on the repertoire of peripheral B-lymphocytes. Cha...
Day 7 post vaccination/day 0 ( D SW d7/ D SW d0) Shannon-Weaver index ratio ( D SW ) for clonotypes ...
Sequencing and repertoire mining metrics with ImmunediveRsity [ 30 ] by vaccination trial and by ind...
CDRH2 sequence in large IGHV1-69 -expressing V H clonotypes. Sequence logos [55] of CDRH2 (IMGT numb...
Serologic analysis of 08/09 TIV and 09 MIV 2009 response. Hemagglutination inhibition assay (HAI) an...
Figure S3. Frequency changes of gene family usage in ASCs comparing to naive B cells. (DOCX 114 kb
Additional file 1: Table S1. Number of mapped reads mapped using BBmap per influenza A and influenza...
Figure S5. Differentially expressed (DE) genes in the chronic Statin-user cohort compared with non-u...
Figure S1. The performance of DSab-origin as somatic hyper-mutation rates increase. (DOCX 73 kb
Figure S1. Serum samples collected on two separate visits following vaccination were tested for IgA,...
(A) rarefection plot: number of sequences is plotted against Chao1 estimator. Error bars indicate SE...
Figure S1. Comparison of the predicted amino acid sequence of PB1-F2 proteins expressed by H3N2 viru...
Effect of B. longum + Gl-OS on levels of vaccine-specific IgA, IgG1, IgD and IgM. Data are optical d...
Reads, clonal groups, and lineages numbers per individual and condition. The table shows the number ...
Figure S6. NGS data on IgG4+ BCR clones. NGS data portraying the frequency of IgG4+ BCR clones (red)...
Per individual effect of immunization with 09 MIV on the repertoire of peripheral B-lymphocytes. Cha...
Day 7 post vaccination/day 0 ( D SW d7/ D SW d0) Shannon-Weaver index ratio ( D SW ) for clonotypes ...
Sequencing and repertoire mining metrics with ImmunediveRsity [ 30 ] by vaccination trial and by ind...
CDRH2 sequence in large IGHV1-69 -expressing V H clonotypes. Sequence logos [55] of CDRH2 (IMGT numb...
Serologic analysis of 08/09 TIV and 09 MIV 2009 response. Hemagglutination inhibition assay (HAI) an...
Figure S3. Frequency changes of gene family usage in ASCs comparing to naive B cells. (DOCX 114 kb
Additional file 1: Table S1. Number of mapped reads mapped using BBmap per influenza A and influenza...
Figure S5. Differentially expressed (DE) genes in the chronic Statin-user cohort compared with non-u...
Figure S1. The performance of DSab-origin as somatic hyper-mutation rates increase. (DOCX 73 kb
Figure S1. Serum samples collected on two separate visits following vaccination were tested for IgA,...
(A) rarefection plot: number of sequences is plotted against Chao1 estimator. Error bars indicate SE...
Figure S1. Comparison of the predicted amino acid sequence of PB1-F2 proteins expressed by H3N2 viru...
Effect of B. longum + Gl-OS on levels of vaccine-specific IgA, IgG1, IgD and IgM. Data are optical d...
Reads, clonal groups, and lineages numbers per individual and condition. The table shows the number ...
Figure S6. NGS data on IgG4+ BCR clones. NGS data portraying the frequency of IgG4+ BCR clones (red)...