Bacterial counts in PBMCs from BCG+ (solid bars) and BCG- (open bars) donors at days 0, 3, 5 and 8 post-infection with Mtb H37Ra. Data were plotted as mean ± SD of 5 samples per group. Experiments were performed in triplicate per condition per donor. **p<0.01, PBMCs from BCG+ donors compared to PBMCs from BCG- donors.</p
<p>(A) Experimental protocol for evaluating the attenuation of MtbΔ<i>mms</i>. (B, C) Bacillary load...
<p>(A) Phylogenetic distribution of the studied Mtb strains within the different subgroups of the Bj...
<p>MØs were infected with FITC-labeled wild-type Mtb or its mutants, Δ(<i>ku,ligD,recA</i>), Δ(<i>ku...
Bacterial counts on days 0, 3, 5 and 8 post-infection. Data were plotted as mean ± SD for 10 donors....
Cytokine concentrations in cell culture supernatants were determined by ELISA at days 0, 3, 5 and 8 ...
Activated CD3+CD4+ and CD3+CD8+ T cell populations of PBMCs from BCG+ donors (solid bars) and BCG- d...
Cytokine concentrations in cell culture supernatants were determined by ELISA for PBMCs infected wit...
Infections of PBMCs from BCG+ donors were associated with lower Mtb H37Ra CFUs, lower concentrations...
This study characterized the immune responses in early Mycobacterium tuberculosis (Mtb) H37Ra infect...
This study characterized the immune responses in early Mycobacterium tuberculosis (Mtb) H37Ra infect...
<p>(A) Schematic outline of the experiments, with antibiotics being added either 1 h (B) after infec...
<p>Matched frequencies of antigen-specific PBs and MBCs were determined by 6-hour ex-vivo and 6-day ...
<p>(<b>A</b>) <b>CFU assay.</b> Growth progression of <i>Mtb</i>-A and reduction of <i>Mtb</i>-H dur...
<p>Frequencies of antigen-specific MBCs were determined by ELISPOT and are presented as a percentage...
<p>THP-1 cells were infected with H37Ra, H37Rv, EAI, LAM and Beijing strains of MTB at MOI of 10 for...
<p>(A) Experimental protocol for evaluating the attenuation of MtbΔ<i>mms</i>. (B, C) Bacillary load...
<p>(A) Phylogenetic distribution of the studied Mtb strains within the different subgroups of the Bj...
<p>MØs were infected with FITC-labeled wild-type Mtb or its mutants, Δ(<i>ku,ligD,recA</i>), Δ(<i>ku...
Bacterial counts on days 0, 3, 5 and 8 post-infection. Data were plotted as mean ± SD for 10 donors....
Cytokine concentrations in cell culture supernatants were determined by ELISA at days 0, 3, 5 and 8 ...
Activated CD3+CD4+ and CD3+CD8+ T cell populations of PBMCs from BCG+ donors (solid bars) and BCG- d...
Cytokine concentrations in cell culture supernatants were determined by ELISA for PBMCs infected wit...
Infections of PBMCs from BCG+ donors were associated with lower Mtb H37Ra CFUs, lower concentrations...
This study characterized the immune responses in early Mycobacterium tuberculosis (Mtb) H37Ra infect...
This study characterized the immune responses in early Mycobacterium tuberculosis (Mtb) H37Ra infect...
<p>(A) Schematic outline of the experiments, with antibiotics being added either 1 h (B) after infec...
<p>Matched frequencies of antigen-specific PBs and MBCs were determined by 6-hour ex-vivo and 6-day ...
<p>(<b>A</b>) <b>CFU assay.</b> Growth progression of <i>Mtb</i>-A and reduction of <i>Mtb</i>-H dur...
<p>Frequencies of antigen-specific MBCs were determined by ELISPOT and are presented as a percentage...
<p>THP-1 cells were infected with H37Ra, H37Rv, EAI, LAM and Beijing strains of MTB at MOI of 10 for...
<p>(A) Experimental protocol for evaluating the attenuation of MtbΔ<i>mms</i>. (B, C) Bacillary load...
<p>(A) Phylogenetic distribution of the studied Mtb strains within the different subgroups of the Bj...
<p>MØs were infected with FITC-labeled wild-type Mtb or its mutants, Δ(<i>ku,ligD,recA</i>), Δ(<i>ku...