Infections of PBMCs from BCG+ donors were associated with lower Mtb H37Ra CFUs, lower concentrations of Th1 and Th2 cytokines, but higher proportions of activated central memory CD8+ T cells compared to infections of BCG- donor PBMCs. Closed square brackets ([]) indicate concentration.</p
<p>(A) Uptake of <i>Mtb</i> H37Rv by PBMC 4 hrs post-infection and intracellular growth 96 hr-post-i...
<p>Whole blood incubated overnight with medium only (I), revealed differences in the concentrations ...
<p>(A) Comparison of the ability of healthy donors and CHB patients to produce IFN-α. PBMCs (2×10<su...
Cytokine concentrations in cell culture supernatants were determined by ELISA at days 0, 3, 5 and 8 ...
Activated CD3+CD4+ and CD3+CD8+ T cell populations of PBMCs from BCG+ donors (solid bars) and BCG- d...
Bacterial counts in PBMCs from BCG+ (solid bars) and BCG- (open bars) donors at days 0, 3, 5 and 8 p...
Cytokine concentrations in cell culture supernatants were determined by ELISA for PBMCs infected wit...
This study characterized the immune responses in early Mycobacterium tuberculosis (Mtb) H37Ra infect...
This study characterized the immune responses in early Mycobacterium tuberculosis (Mtb) H37Ra infect...
<p><b>(a)</b> eFluor450 dilution by memory (Thy1.1<sup>+/+</sup>, 1<sup>st</sup> column) or naive (T...
<p>Primary human (<b>A</b>) MDM or (<b>B</b>) AM were infected with <i>MTB</i> H37Rv and after 1 hr,...
<p><b>(a)</b> Experimental strategy for adoptive co-transfer experiments. Relative proportion of naï...
<p>The graph shows the proliferation of healthy donor peripheral blood mononuclear cells (HD-PBMCs) ...
<p>(A–C) BCG-vaccinated or age-matched naïve mice were infected with <i>Mtb</i> Erdman, and 6 weeks ...
<p>(A) PBECs were co-cultured with infected or uninfected THP-1 cells in the presence of αL1β or IgG...
<p>(A) Uptake of <i>Mtb</i> H37Rv by PBMC 4 hrs post-infection and intracellular growth 96 hr-post-i...
<p>Whole blood incubated overnight with medium only (I), revealed differences in the concentrations ...
<p>(A) Comparison of the ability of healthy donors and CHB patients to produce IFN-α. PBMCs (2×10<su...
Cytokine concentrations in cell culture supernatants were determined by ELISA at days 0, 3, 5 and 8 ...
Activated CD3+CD4+ and CD3+CD8+ T cell populations of PBMCs from BCG+ donors (solid bars) and BCG- d...
Bacterial counts in PBMCs from BCG+ (solid bars) and BCG- (open bars) donors at days 0, 3, 5 and 8 p...
Cytokine concentrations in cell culture supernatants were determined by ELISA for PBMCs infected wit...
This study characterized the immune responses in early Mycobacterium tuberculosis (Mtb) H37Ra infect...
This study characterized the immune responses in early Mycobacterium tuberculosis (Mtb) H37Ra infect...
<p><b>(a)</b> eFluor450 dilution by memory (Thy1.1<sup>+/+</sup>, 1<sup>st</sup> column) or naive (T...
<p>Primary human (<b>A</b>) MDM or (<b>B</b>) AM were infected with <i>MTB</i> H37Rv and after 1 hr,...
<p><b>(a)</b> Experimental strategy for adoptive co-transfer experiments. Relative proportion of naï...
<p>The graph shows the proliferation of healthy donor peripheral blood mononuclear cells (HD-PBMCs) ...
<p>(A–C) BCG-vaccinated or age-matched naïve mice were infected with <i>Mtb</i> Erdman, and 6 weeks ...
<p>(A) PBECs were co-cultured with infected or uninfected THP-1 cells in the presence of αL1β or IgG...
<p>(A) Uptake of <i>Mtb</i> H37Rv by PBMC 4 hrs post-infection and intracellular growth 96 hr-post-i...
<p>Whole blood incubated overnight with medium only (I), revealed differences in the concentrations ...
<p>(A) Comparison of the ability of healthy donors and CHB patients to produce IFN-α. PBMCs (2×10<su...