Additional file 1: of Blood-brain barrier-associated pericytes internalize and clear aggregated amyloid-β42 by LRP1-dependent apolipoprotein E isoform-specific mechanism
- Qingyi Ma (5875343)
- Zhen Zhao (159931)
- Abhay Sagare (5875349)
- Yingxi Wu (5875355)
- Min Wang (21070)
- Nelly Owens (5875361)
- Philip Verghese (3483140)
- Joachim Herz (28421)
- David Holtzman (449599)
- Berislav Zlokovic (3999767)
Publication date
October 2018
DOIAbstract
Table S1. Demographic and clinical features of human subjects used in this study. Figure S1. Aβ deposition in microvessels in AD patients and APPSw/0 mice. Figure S2. Biochemical analysis of Aβ42 aggregates. Figure S3. Cy3-Aβ42 cellular uptake in wild type mouse brain slices within 30 min. Figure S4. Pericyte coverages in Lrp1lox/lox and Lrp1lox/lox; Cspg4-Cre mice. Figure S5.. LRP1 and apoE suppression with siRNA. (DOCX 1454 kb
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