The ratio of mouse apoE to human apoE4 within different amyloid lesions in 10 month old 5XFAD/apoEm/4 brains shown in Fig. 2 and Fig. 3 (n = 8/group; ***, p < 0.001; One-way ANOVA repeated measures). (TIF 174 kb
Western blot analysis of A brain-derived neurotrophic factor (BDNF), B Growth associated protein 43 ...
Figure S1. Representative low magnification images demonstrate that amyloid deposition is predominan...
Comparative analysis of Aβ plaque load immunostained against N-terminal and central Aβ epitopes reve...
Aβ plaque onset age in 5XFAD/apoEm/m and 5XFAD/apoE4/4 brain. Aβ immunostaining was performed using ...
Specific antibodies for mouse apoE and human apoE4 immunostaining. 5XFAD/apoEm/m and 5XFAD/apoE4/4 b...
Specific ELISA for mouse apoE and human apoE. a Mouse apoE was detected by using HJ6.2 as the captur...
Lack of amyloid plaque deposition at 3 months. (A) Thioflavin-S staining confirms absence of amyloid...
Table S1. Demographic and clinical features of human subjects used in this study. Figure S1. Aβ depo...
Radial distribution around arteries is greater for non-lipidated than lapidated apoE4. A-H) Represen...
Figure S2. (A) Quantification of amyloid plaque load (% of total ROI area) in male (M) and female (F...
Synaptophysin and MAP2 immunostaining in the hippocampus. (a)Enlarged view of synaptophysin staining...
No difference in APP processing at 8 months. (A) Western blot analysis of cortical SDS extracts from...
Figure S1. Survival rates for (a) female and (b) male mice with known genotype upon death or experim...
Laboratory names and line designations of the transgenic mice used. Figure S1. Comparison of APP exp...
Additional file 3: Figure sup 3. Similar levels of astrogliosis were observed in apoE-TR mice upon c...
Western blot analysis of A brain-derived neurotrophic factor (BDNF), B Growth associated protein 43 ...
Figure S1. Representative low magnification images demonstrate that amyloid deposition is predominan...
Comparative analysis of Aβ plaque load immunostained against N-terminal and central Aβ epitopes reve...
Aβ plaque onset age in 5XFAD/apoEm/m and 5XFAD/apoE4/4 brain. Aβ immunostaining was performed using ...
Specific antibodies for mouse apoE and human apoE4 immunostaining. 5XFAD/apoEm/m and 5XFAD/apoE4/4 b...
Specific ELISA for mouse apoE and human apoE. a Mouse apoE was detected by using HJ6.2 as the captur...
Lack of amyloid plaque deposition at 3 months. (A) Thioflavin-S staining confirms absence of amyloid...
Table S1. Demographic and clinical features of human subjects used in this study. Figure S1. Aβ depo...
Radial distribution around arteries is greater for non-lipidated than lapidated apoE4. A-H) Represen...
Figure S2. (A) Quantification of amyloid plaque load (% of total ROI area) in male (M) and female (F...
Synaptophysin and MAP2 immunostaining in the hippocampus. (a)Enlarged view of synaptophysin staining...
No difference in APP processing at 8 months. (A) Western blot analysis of cortical SDS extracts from...
Figure S1. Survival rates for (a) female and (b) male mice with known genotype upon death or experim...
Laboratory names and line designations of the transgenic mice used. Figure S1. Comparison of APP exp...
Additional file 3: Figure sup 3. Similar levels of astrogliosis were observed in apoE-TR mice upon c...
Western blot analysis of A brain-derived neurotrophic factor (BDNF), B Growth associated protein 43 ...
Figure S1. Representative low magnification images demonstrate that amyloid deposition is predominan...
Comparative analysis of Aβ plaque load immunostained against N-terminal and central Aβ epitopes reve...