Mmm1 overproduction leads to increased peroxisome population in wild-type cells while <i>MMM1</i> deletion restores wild-type level of peroxisomes in <i>mdm12Δ</i> cells.

(A) Percentage of cells for a given number of peroxisomes per cell is shown for the wild-type strain expressing or not (-) MMM1 from its own promoter (MMM1) or from the strong PGK1 promoter (OE-MMM1). (*) indicates that the difference in average number of peroxisomes per cell is significant relative to the reference strains, after statistical analyses (Student’s t test, p-values mdm10Δ and mdm12Δ mutants or in the double mdm10Δmmm1Δ and mdm12Δmmm1Δ mutants. For each strain, the number of peroxisomes was counted from images of two counts of at least 100 non-budding cells from two independent experiments. On each graph, the average number (± SD) of peroxisomes is indicated. (*) indicates that the difference in average number of peroxisomes per cell is significant relative to the single mutant strains, after statistical analyses (Student’s t test, p-values < 0.005).