The concentration of total RSV in the supernatant quantified via qRT-PCR (vRNAe/mL) at 14 dpi for infections performed in duplicate is shown as a function of the MOI of the inoculum deposited onto the SIAT cells (TCID69/cell). The relation shown (solid line) corresponds to log10(y) = log10(x) + b where b = 9.3 ± 0.8 and R2 is as shown. The total number of RSV progeny produced over the course of the infections is approximately proportional to inoculating MOI. Duplicate measures (two symbols) rather than error bars are plotted at each sampling time point, through in some cases only one point is visible.</p
(A) Diagram showing how cbVGs form during negative-sense single-stranded RNA virus infection. (B) Ag...
Comparison of the rate of loss of virus infectivity at 37°C for (A) influenza A (H1N1) virus (A/New ...
<p>A, Proportion of MLN containing infectious RRV. The numbers of mice analysed on each day are give...
SIAT cells were infected in duplicate with 3 different dilutions (MOIs) of an RSV A Long inoculum. O...
Comparison of the infectivity of individual RSV samples as measured on SIAT cells in TCID69/mL compa...
Parameters of the in silico MMs (lines) Eqs (9)–(11) were estimated by simultaneously considering al...
<p><b>Panels A</b>, PHBE cells, were treated with 10% Ino-RNA (20 µg/ml for), N-RNA (20 µg/ml), or I...
<p>(A). Gradient purifier RSV (∼10<sup>5</sup> particles/50 µl) was resolved on the SDS-PAGE, follow...
<p>10<sup>6</sup> or 10<sup>4</sup> cells were transferred into mice at input ratios of 2:1, 1:1, an...
<p>Most experiments in this study were conducted using 24-well tissue culture plates and nearly 100%...
(A) SG (G3BP1, magenta) and viral protein (RSV NP, yellow) detection 12 and 24 hpi with RSV cbVG-hig...
<p>A549 cells were infected with RSV A2 GFP at MOI 0.1 and treated with DMSO or TVB-3166 as indicate...
<p>Quantification of RSV replication via RT-qPCR and infectious focus assay in lambs inoculated with...
<p>A549 cells were infected with RSV A2 GFP at MOI 0.3 and treated with DMSO or 0.2 μM TVB-3166 as s...
Many aspects of the respiratory syncytial virus (RSV) are still poorly understood. Yet these knowled...
(A) Diagram showing how cbVGs form during negative-sense single-stranded RNA virus infection. (B) Ag...
Comparison of the rate of loss of virus infectivity at 37°C for (A) influenza A (H1N1) virus (A/New ...
<p>A, Proportion of MLN containing infectious RRV. The numbers of mice analysed on each day are give...
SIAT cells were infected in duplicate with 3 different dilutions (MOIs) of an RSV A Long inoculum. O...
Comparison of the infectivity of individual RSV samples as measured on SIAT cells in TCID69/mL compa...
Parameters of the in silico MMs (lines) Eqs (9)–(11) were estimated by simultaneously considering al...
<p><b>Panels A</b>, PHBE cells, were treated with 10% Ino-RNA (20 µg/ml for), N-RNA (20 µg/ml), or I...
<p>(A). Gradient purifier RSV (∼10<sup>5</sup> particles/50 µl) was resolved on the SDS-PAGE, follow...
<p>10<sup>6</sup> or 10<sup>4</sup> cells were transferred into mice at input ratios of 2:1, 1:1, an...
<p>Most experiments in this study were conducted using 24-well tissue culture plates and nearly 100%...
(A) SG (G3BP1, magenta) and viral protein (RSV NP, yellow) detection 12 and 24 hpi with RSV cbVG-hig...
<p>A549 cells were infected with RSV A2 GFP at MOI 0.1 and treated with DMSO or TVB-3166 as indicate...
<p>Quantification of RSV replication via RT-qPCR and infectious focus assay in lambs inoculated with...
<p>A549 cells were infected with RSV A2 GFP at MOI 0.3 and treated with DMSO or 0.2 μM TVB-3166 as s...
Many aspects of the respiratory syncytial virus (RSV) are still poorly understood. Yet these knowled...
(A) Diagram showing how cbVGs form during negative-sense single-stranded RNA virus infection. (B) Ag...
Comparison of the rate of loss of virus infectivity at 37°C for (A) influenza A (H1N1) virus (A/New ...
<p>A, Proportion of MLN containing infectious RRV. The numbers of mice analysed on each day are give...