RRV replication and T cell subsets in the MLN of RRV-infected infant mice.

<p>A, Proportion of MLN containing infectious RRV. The numbers of mice analysed on each day are given in the Legend to Fig. 1A. Absolute numbers of CD4⁺ TCRαβ T cells (B) and CD8αβ TCRαβ T cells (C) at day 2 post infection are shown. To obtain sufficient cells, 4 to 5 separate cell pools were analysed for each inoculum. Each pool was produced from 4 to 5 (NOD), 3 to 4 (BALB/c) or 3 to 5 (C57BL/6) mice. Cell numbers from pools were normalized to represent cells obtained from a single mouse. D, Absolute numbers of CD3⁺, CD8⁺ and CD4⁺ T cells from RRV-infected mice at day 6 post infection. Each data point represents a pool of cells from 4 (NOD), 3 (BALB/c) or 3 to 4 (C57BL/6) mice. * p<0.05; ** p<0.01. Bar = mean.