Weight (g) in control and dystrophic mice during the treatment period.

C57BL/10 mice (Ctrl; black line), saline-treated mdx mice (mdxS; blue line), prednisolone-treated mdx mice (mdxP; red line) and Tempol-treated mdx mice (mdxT; green line). All values expressed as mean ± standard deviation (SD). *P ≤ 0.05 compared with Ctrl group, **P ≤ 0.001 compared with Ctrl group, ***P ≤ 0.0001 compared with Ctrl group, #P ≤ 0.05 compared with mdxS group, ##P ≤ 0.001 compared with mdxS group, ††P ≤ 0.001 compared with mdxP group, †††P ≤ 0.0001 compared with mdxP group (one-way ANOVA with Tukey’s post-hoc test).