<p>Assessment of severity in controls (A, B) and DSS treated mice (1% DSS C, D and 1.5% DSS E, F) determined by an overall clinical disease activity score (A, C, E) and specifically by the change in body weight (B, D, F). Untreated controls exhibited low clinical scores (A) and a steady body weight (B). Mice treated with 1% (C, D) or 1.5% DSS (E, F) demonstrated increasing clinical scores and loss of body weight. <i>Cd14</i><sup><i>-/-</i></sup> mice showed significantly higher clinical scores and a significantly higher reduction of body weight than WT mice.</p
<p><i>Smad3<sup>+/−</sup></i>, <i>Smad3<sup>−/−</sup></i> and <i>Smad3/Rag-DKO</i> (DKO) mice were t...
(a) Determination of body weight (% change from baseline) and (b) WR20 (percent change from baseline...
Longitudinal trends in climbing (A), locomotion (B) and immobility (C) were measured pre-operatively...
<p>A, Percentage of body weight loss over the course of 5 days of treatment with 2.0% DSS water foll...
<p>(A) Change in body weight. Percent weight loss from baseline (y-axis) is plotted versus time post...
(A) The body weight loss of mice in each group for 8 consecutive days (n = 6). (B) The change of dis...
<p><b>A</b>. Body weight change from day 1 to day 8. Each bar represents the average body weight cha...
<p>C57BL/6 mice were administered to 3.5% DSS by drinking water for indicated days. Body weight chan...
<p>Mice were treated with both DSS and OVA for 6 days, and several clinical parameters were measured...
<p>WT or Rag KO mice were fed the experimental diets for 2% DSS treatment and throughout the experim...
<p>The <i>clinical disease score</i> (CDS) as applied in our study to score signs of disease in indi...
<p>Wild-type and CD38<sup>-/-</sup> mice were treated with DSS as in <a href="http://www.plosone.org...
<p>Wildtype (WT) and TRPA1 knock-out (KO) mice were orally administered 2% dextran-sulfate (DSS) and...
<p>(A) Mouse body weight changes during DSS treatment compared to that of control animals (drinking ...
<p>(A) Body weight, (B) body weight changes, (C) spleen weight, (D) spleen/body weight, (E) colon le...
<p><i>Smad3<sup>+/−</sup></i>, <i>Smad3<sup>−/−</sup></i> and <i>Smad3/Rag-DKO</i> (DKO) mice were t...
(a) Determination of body weight (% change from baseline) and (b) WR20 (percent change from baseline...
Longitudinal trends in climbing (A), locomotion (B) and immobility (C) were measured pre-operatively...
<p>A, Percentage of body weight loss over the course of 5 days of treatment with 2.0% DSS water foll...
<p>(A) Change in body weight. Percent weight loss from baseline (y-axis) is plotted versus time post...
(A) The body weight loss of mice in each group for 8 consecutive days (n = 6). (B) The change of dis...
<p><b>A</b>. Body weight change from day 1 to day 8. Each bar represents the average body weight cha...
<p>C57BL/6 mice were administered to 3.5% DSS by drinking water for indicated days. Body weight chan...
<p>Mice were treated with both DSS and OVA for 6 days, and several clinical parameters were measured...
<p>WT or Rag KO mice were fed the experimental diets for 2% DSS treatment and throughout the experim...
<p>The <i>clinical disease score</i> (CDS) as applied in our study to score signs of disease in indi...
<p>Wild-type and CD38<sup>-/-</sup> mice were treated with DSS as in <a href="http://www.plosone.org...
<p>Wildtype (WT) and TRPA1 knock-out (KO) mice were orally administered 2% dextran-sulfate (DSS) and...
<p>(A) Mouse body weight changes during DSS treatment compared to that of control animals (drinking ...
<p>(A) Body weight, (B) body weight changes, (C) spleen weight, (D) spleen/body weight, (E) colon le...
<p><i>Smad3<sup>+/−</sup></i>, <i>Smad3<sup>−/−</sup></i> and <i>Smad3/Rag-DKO</i> (DKO) mice were t...
(a) Determination of body weight (% change from baseline) and (b) WR20 (percent change from baseline...
Longitudinal trends in climbing (A), locomotion (B) and immobility (C) were measured pre-operatively...