WB ICS Ag85A-specific CD4+ T cells positive for IFNγ (a), TNFα (b), IL2 (c), and IL17 (d) and CD8+ T cells positive for IFNγ (e) and TNFα (f). X axis = time points in days, Y axis = percent of CD4+ or CD8+ T cells positive for that cytokine. Statistically significant differences from baseline and between groups are shown. Non-significant differences (p > 0.05) are omitted for clarity. *p p p Y axis scales. Ag85A, antigen 85A; ICS, intracellular cytokine staining; WB, whole blood.</p
<p>The IFNγ cytokine profile of CD4<sup>+</sup> and CD8<sup>+</sup> T-cells was analyzed by ICS. In ...
<p>We carried out multi-parameter ICS at week 3 after the rAd5 immunization to determine the ability...
<p>Whole blood was incubated for 12 hours with the antigen BCG to measure proportions of IFN-γ, IL-2...
X axis = time points in days, Y axis = percent of CD4+ (a and b) or CD8+ T (c and d) cells positive ...
BAL Ag85A-specific CD4+ T cells positive for IFNγ (a), TNFα (b), IL2 (c), and IL17 (d) and Ag85A-spe...
(a) CD4+ IFNγ+ TNFα+ IL2+ IL17+; (b) CD4+ IFNγ+ TNFα+ IL2+, (c) CD4+ IFNγ+ TNFα+ IL17+; (d) CD4+ IFN...
<p>(A) CD4+ response rates. (B) CD4+ response magnitude. (C) CD8+ response rate. (D) CD8+ response m...
Frequency of antigen-specific IFNγ secreting cells to (a–c) Ag85A peptides (top row), (d–f) MVA CD4 ...
<p><b>A</b> & <b>B</b>) Pie charts represent the proportion of CD4<sup>+</sup> T cells (<b>A</b>) or...
<p>A. Geometric mean CS-specific CD4<sup>+</sup> T cells producing IFN-γ by ELISpot. Comparisons bet...
<p>(A) Magnitude of T cell cytokine responses to JEV SA14-14-2 detected by flow cytometry/ICS in fiv...
BAL MVA-specific CD4+ T cell responses (a and b) and CD8+ T cell responses (c and d) positive for cy...
<p>Mean percent and standard error of the mean (SEM) of CD4+ and CD8+ PBMCs producing antigen-specif...
<p>(<b>A</b>) Representative dot plots of gating strategy used and cytokine responses detected using...
<p>One week after the second and final immunization splenocytes were analyzed for intracellular cyto...
<p>The IFNγ cytokine profile of CD4<sup>+</sup> and CD8<sup>+</sup> T-cells was analyzed by ICS. In ...
<p>We carried out multi-parameter ICS at week 3 after the rAd5 immunization to determine the ability...
<p>Whole blood was incubated for 12 hours with the antigen BCG to measure proportions of IFN-γ, IL-2...
X axis = time points in days, Y axis = percent of CD4+ (a and b) or CD8+ T (c and d) cells positive ...
BAL Ag85A-specific CD4+ T cells positive for IFNγ (a), TNFα (b), IL2 (c), and IL17 (d) and Ag85A-spe...
(a) CD4+ IFNγ+ TNFα+ IL2+ IL17+; (b) CD4+ IFNγ+ TNFα+ IL2+, (c) CD4+ IFNγ+ TNFα+ IL17+; (d) CD4+ IFN...
<p>(A) CD4+ response rates. (B) CD4+ response magnitude. (C) CD8+ response rate. (D) CD8+ response m...
Frequency of antigen-specific IFNγ secreting cells to (a–c) Ag85A peptides (top row), (d–f) MVA CD4 ...
<p><b>A</b> & <b>B</b>) Pie charts represent the proportion of CD4<sup>+</sup> T cells (<b>A</b>) or...
<p>A. Geometric mean CS-specific CD4<sup>+</sup> T cells producing IFN-γ by ELISpot. Comparisons bet...
<p>(A) Magnitude of T cell cytokine responses to JEV SA14-14-2 detected by flow cytometry/ICS in fiv...
BAL MVA-specific CD4+ T cell responses (a and b) and CD8+ T cell responses (c and d) positive for cy...
<p>Mean percent and standard error of the mean (SEM) of CD4+ and CD8+ PBMCs producing antigen-specif...
<p>(<b>A</b>) Representative dot plots of gating strategy used and cytokine responses detected using...
<p>One week after the second and final immunization splenocytes were analyzed for intracellular cyto...
<p>The IFNγ cytokine profile of CD4<sup>+</sup> and CD8<sup>+</sup> T-cells was analyzed by ICS. In ...
<p>We carried out multi-parameter ICS at week 3 after the rAd5 immunization to determine the ability...
<p>Whole blood was incubated for 12 hours with the antigen BCG to measure proportions of IFN-γ, IL-2...