Frequency of antigen-specific IFNγ secreting cells to (a–c) Ag85A peptides (top row), (d–f) MVA CD4 peptides (middle row), and (g–i) MVA CD8 peptides (bottom row) in Group 1 (left column), Group 2 (middle column), and Group 3 (right column). X axis: time points in days, Y axis: SFC per 1 × 106 PBMCs. Shown are significant differences from baseline (day 0). Non-significant differences (p > 0.05) omitted for clarity. *p p p < 0.001. Ag85A, antigen 85A; MVA, modified vaccinia virus Ankara; PBMC, peripheral blood mononuclear cell; SPC, spot forming cells.</p
Frequencies of (A) KI67+ ASCs [CD19+CD10-IgD-CD71+CD38+CD20-], (B) IgG+ ASCs, and (C) IgA+ ASCs, ide...
<p>Dot plots showing individual cytokine responses in subjects from active VL (n = 8), cured VL (n =...
Responses against Ag85A (a–c) and MVA (d–f) for Groups 1, 2, and 3 (from left to right). X axis = ti...
X axis = time points in days, Y axis = percent of CD4+ (a and b) or CD8+ T (c and d) cells positive ...
WB ICS Ag85A-specific CD4+ T cells positive for IFNγ (a), TNFα (b), IL2 (c), and IL17 (d) and CD8+ T...
<p>(A, D), uCD4i, (B, E), and uCD8i (C, F) epitope library. Top row represents differences among cas...
<p>The frequency of IFNγ producers in PBMC, as determined by ELISpot, from animals immunised with BC...
<p>The box plots (see Statistical Analysis section for description) represent IFN-γ -producing CD4+ ...
4a. IFN-γ spot forming units (SFU) per million cells (ELISpot) from PBMC stimulated with SARS-CoV-2 ...
<p>PBMC were obtained at the indicated time points from RTS,S-immunized subjects and were incubated ...
<p>Average magnitude of IFN-γ ELISPOT responses in SFC/10<sup>6</sup> cells (Y-axis) at each time po...
<p>Graphs represent the frequency of IFN-γ<sup>+</sup> CD4<sup>+</sup> T cells (<b>A</b>) or CD8<sup...
<p>The panels show individual background-subtracted IFN-γ ELISPOT counts to each antigen at 2 weeks ...
<p>A. Geometric mean CS-specific CD4<sup>+</sup> T cells producing IFN-γ by ELISpot. Comparisons bet...
<p>The panels show the percentage of T-cells releasing IFN-γ (A) and IL-2 (B) for CD4+ T-cells, and ...
Frequencies of (A) KI67+ ASCs [CD19+CD10-IgD-CD71+CD38+CD20-], (B) IgG+ ASCs, and (C) IgA+ ASCs, ide...
<p>Dot plots showing individual cytokine responses in subjects from active VL (n = 8), cured VL (n =...
Responses against Ag85A (a–c) and MVA (d–f) for Groups 1, 2, and 3 (from left to right). X axis = ti...
X axis = time points in days, Y axis = percent of CD4+ (a and b) or CD8+ T (c and d) cells positive ...
WB ICS Ag85A-specific CD4+ T cells positive for IFNγ (a), TNFα (b), IL2 (c), and IL17 (d) and CD8+ T...
<p>(A, D), uCD4i, (B, E), and uCD8i (C, F) epitope library. Top row represents differences among cas...
<p>The frequency of IFNγ producers in PBMC, as determined by ELISpot, from animals immunised with BC...
<p>The box plots (see Statistical Analysis section for description) represent IFN-γ -producing CD4+ ...
4a. IFN-γ spot forming units (SFU) per million cells (ELISpot) from PBMC stimulated with SARS-CoV-2 ...
<p>PBMC were obtained at the indicated time points from RTS,S-immunized subjects and were incubated ...
<p>Average magnitude of IFN-γ ELISPOT responses in SFC/10<sup>6</sup> cells (Y-axis) at each time po...
<p>Graphs represent the frequency of IFN-γ<sup>+</sup> CD4<sup>+</sup> T cells (<b>A</b>) or CD8<sup...
<p>The panels show individual background-subtracted IFN-γ ELISPOT counts to each antigen at 2 weeks ...
<p>A. Geometric mean CS-specific CD4<sup>+</sup> T cells producing IFN-γ by ELISpot. Comparisons bet...
<p>The panels show the percentage of T-cells releasing IFN-γ (A) and IL-2 (B) for CD4+ T-cells, and ...
Frequencies of (A) KI67+ ASCs [CD19+CD10-IgD-CD71+CD38+CD20-], (B) IgG+ ASCs, and (C) IgA+ ASCs, ide...
<p>Dot plots showing individual cytokine responses in subjects from active VL (n = 8), cured VL (n =...
Responses against Ag85A (a–c) and MVA (d–f) for Groups 1, 2, and 3 (from left to right). X axis = ti...