IFN-γ, TNF-α and IL-10 responses to peptide pools for 5 novel antigens.

<p>Dot plots showing individual cytokine responses in subjects from active VL (n = 8), cured VL (n = 16), EHC^+ve (n = 20) and EHC^−ve (n = 9) groups 24 hours post stimulation of whole blood assays with peptide pools (5 µg/mL) for the 5 antigens R71, L37, N52, J41, and M22. Data are presented for each cytokine response (A–E IFN-γ; F–J TNF-α; K–O IL-10). Bars indicate the mean group response. Antigen-stimulated cytokine responses are provided after subtraction of the non-stimulated control wells. Statistical differences between groups determined using the non-parametric Man-Whitney test are indicated by bars above columns, * indicates p<0.05, ** p<0.01, and *** p<0.001. Data for 72 hours and 6 days post stimulation are presented in <a href="http://www.plosntds.org/article/info:doi/10.1371/journal.pntd.0001874#pntd.0001874.s004" target="_blank">Fig. S4</a> and <a href="http://www.plosntds.org/article/info:doi/10.1371/journal.pntd.0001874#pntd.0001874.s005" target="_blank">Fig. S5</a>, respectively.