Phenotype of long-term siRNA treated cells.

<p>When seeded at the same density for 5 days without treatment, BT474-TNP-H30 grew slower than parental BT474 and other derivatives. Images showing representative fields at 100X magnification <b>(A)</b>. Fold change in nuclei count after 5 days of growth <b>(B)</b> and the corresponding doubling time <b>(C)</b>. Bars represent mean ± SD of 6 replicates in a 96-well plate. Asterisks * indicate statistical significance when compared to the parental BT474 (P < 0.05).