<p>Large pial deposits (A), deposits associated with leptomeningeal blood vessels (B), perivascular deposits in corpus callosum (C) and white matter cerebellum (D) were observed in 263K<sup>(M)H</sup> group. The animals of 263K<sup>(MH)</sup> showed perivascular (black arrow) and stellate (red arrows) deposits in hippocampus (E,F). Scale bar = 200 μm (A-E).</p
<p>Each tissue is presented as a pair, tg44 on top and WT on the bottom. Tissue sections were staine...
<p>Patterns of PrP<sup>Sc</sup> deposition in the brain following first (left column) and second (ri...
<p>Panels A, E, I and M, schematics showing regional distribution of abnormal PrP deposits. Note tha...
<p>Representative images of the frontal cortex, hippocampus, thalamus, caudate-putamen, or cerebellu...
<p>On the left, the purple and red areas on the schematic coronal brain sections designate regions w...
<p>(a) At 150 dpi, small quantities of fine-punctate misfolded PrP deposits can be detected in the m...
<p>(<b>A</b>) First column: Paraffin-embedded tissue (PET) blots demonstrating PrP<sup>Sc</sup> depo...
<p>The 22L scrapie-infected anchorless PrP tg44+/+ mouse shown was clinically positive at 377 dpi. (...
<p>Representative images of caudate putamen (<b>a</b>) and cerebellum (<b>b</b>) stained with hemato...
<p>(<b>A</b>) First column: Paraffin-embedded tissue (PET) blots demonstrating PrP<sup>Sc</sup> depo...
<p>Representative images of the frontal cortex, hippocampus, thalamus, caudate-putamen, or cerebellu...
<p>Patterns of PrP-d accumulation in brains of wild-type CD-1 mice i.p. challenged with rec-Prions. ...
<p>Representative images of the frontal cortex, hippocampus, thalamus, caudate-putamen, or cerebellu...
<p>Representative images of the frontal cortex (<b>a, b, c, d</b>) and hippocampus (<b>e, f, g, h</b...
<p>Representative images of coronal brain sections are shown. From left to right: septal level, hipp...
<p>Each tissue is presented as a pair, tg44 on top and WT on the bottom. Tissue sections were staine...
<p>Patterns of PrP<sup>Sc</sup> deposition in the brain following first (left column) and second (ri...
<p>Panels A, E, I and M, schematics showing regional distribution of abnormal PrP deposits. Note tha...
<p>Representative images of the frontal cortex, hippocampus, thalamus, caudate-putamen, or cerebellu...
<p>On the left, the purple and red areas on the schematic coronal brain sections designate regions w...
<p>(a) At 150 dpi, small quantities of fine-punctate misfolded PrP deposits can be detected in the m...
<p>(<b>A</b>) First column: Paraffin-embedded tissue (PET) blots demonstrating PrP<sup>Sc</sup> depo...
<p>The 22L scrapie-infected anchorless PrP tg44+/+ mouse shown was clinically positive at 377 dpi. (...
<p>Representative images of caudate putamen (<b>a</b>) and cerebellum (<b>b</b>) stained with hemato...
<p>(<b>A</b>) First column: Paraffin-embedded tissue (PET) blots demonstrating PrP<sup>Sc</sup> depo...
<p>Representative images of the frontal cortex, hippocampus, thalamus, caudate-putamen, or cerebellu...
<p>Patterns of PrP-d accumulation in brains of wild-type CD-1 mice i.p. challenged with rec-Prions. ...
<p>Representative images of the frontal cortex, hippocampus, thalamus, caudate-putamen, or cerebellu...
<p>Representative images of the frontal cortex (<b>a, b, c, d</b>) and hippocampus (<b>e, f, g, h</b...
<p>Representative images of coronal brain sections are shown. From left to right: septal level, hipp...
<p>Each tissue is presented as a pair, tg44 on top and WT on the bottom. Tissue sections were staine...
<p>Patterns of PrP<sup>Sc</sup> deposition in the brain following first (left column) and second (ri...
<p>Panels A, E, I and M, schematics showing regional distribution of abnormal PrP deposits. Note tha...