<p>Representative images of the frontal cortex, hippocampus, thalamus, caudate-putamen, or cerebellum stained with anti-PrP SAF-84 or anti-GFAP antibodies as indicated. Scale bar = 100 μm for all images.</p
<p>(A) Frontal cortex (10×) section with severe encephalitic changes including perivascular lymphohi...
<p>(A–B) Immunohistochemical staining of mouse P70 brain for Gfapδ (1), pan-Gfap (2), Vimentin (3) a...
<p>(<b>A</b>) First column: Paraffin-embedded tissue (PET) blots demonstrating PrP<sup>Sc</sup> depo...
<p>Representative images of the frontal cortex, hippocampus, thalamus, caudate-putamen, or cerebellu...
<p>Representative images of the frontal cortex, hippocampus, thalamus, caudate-putamen, or cerebellu...
<p>Representative images of caudate putamen (<b>a</b>) and cerebellum (<b>b</b>) stained with hemato...
<p>Representative images of the frontal cortex (<b>a, b, c, d</b>) and hippocampus (<b>e, f, g, h</b...
<p>Large pial deposits (A), deposits associated with leptomeningeal blood vessels (B), perivascular ...
<p>The coronal sections shown are at approximately the same anatomical level (left panels 1.98 mm an...
<p>GFAP-positive cells (A, B, C, D; brains stem; brown) are significantly higher in number in all le...
<p>(<b>A</b>) Histology of cerebellum of <i>BCCIP-CON</i> (top row) and <i>BCCIP-CKD</i> (bottom row...
<p>(A–D) Nissl staining of sagittal sections of WT and <i>Dab2IP</i> KD cerebella at P0, P8, P14 and...
<p>Panels A, E, I and M, schematics showing regional distribution of abnormal PrP deposits. Note tha...
<p>(A) Photographs of the whole brains of two-week-old (a) and twenty-week-old (b) mice. The brain o...
<p>Shown in the upper bar graphs are the comparisons in optical density (mean ± SE) of immunostainin...
<p>(A) Frontal cortex (10×) section with severe encephalitic changes including perivascular lymphohi...
<p>(A–B) Immunohistochemical staining of mouse P70 brain for Gfapδ (1), pan-Gfap (2), Vimentin (3) a...
<p>(<b>A</b>) First column: Paraffin-embedded tissue (PET) blots demonstrating PrP<sup>Sc</sup> depo...
<p>Representative images of the frontal cortex, hippocampus, thalamus, caudate-putamen, or cerebellu...
<p>Representative images of the frontal cortex, hippocampus, thalamus, caudate-putamen, or cerebellu...
<p>Representative images of caudate putamen (<b>a</b>) and cerebellum (<b>b</b>) stained with hemato...
<p>Representative images of the frontal cortex (<b>a, b, c, d</b>) and hippocampus (<b>e, f, g, h</b...
<p>Large pial deposits (A), deposits associated with leptomeningeal blood vessels (B), perivascular ...
<p>The coronal sections shown are at approximately the same anatomical level (left panels 1.98 mm an...
<p>GFAP-positive cells (A, B, C, D; brains stem; brown) are significantly higher in number in all le...
<p>(<b>A</b>) Histology of cerebellum of <i>BCCIP-CON</i> (top row) and <i>BCCIP-CKD</i> (bottom row...
<p>(A–D) Nissl staining of sagittal sections of WT and <i>Dab2IP</i> KD cerebella at P0, P8, P14 and...
<p>Panels A, E, I and M, schematics showing regional distribution of abnormal PrP deposits. Note tha...
<p>(A) Photographs of the whole brains of two-week-old (a) and twenty-week-old (b) mice. The brain o...
<p>Shown in the upper bar graphs are the comparisons in optical density (mean ± SE) of immunostainin...
<p>(A) Frontal cortex (10×) section with severe encephalitic changes including perivascular lymphohi...
<p>(A–B) Immunohistochemical staining of mouse P70 brain for Gfapδ (1), pan-Gfap (2), Vimentin (3) a...
<p>(<b>A</b>) First column: Paraffin-embedded tissue (PET) blots demonstrating PrP<sup>Sc</sup> depo...