Additional file 1: of Transcriptional profiling and biomarker identification reveal tissue specific effects of expanded ataxin-3 in a spinocerebellar ataxia type 3 mouse model

Additional file 3: of Bortezomib treatment induces a higher mortality rate in lupus model mice with a higher disease activity

Tomoko Ikeda (816958)
Hiroshi Fujii (289510)
Masato Nose (1272312)
Yukiko Kamogawa (4351870)
Tsuyoshi Shirai (3938939)
Yuko Shirota (4351867)
Tomonori Ishii (186302)
Hideo Harigae (133506)

August 2017

is a table presenting significantly increased or decreased genes among the proteasome ubiquitin path...

Additional file 4: of Nascent RNA sequencing analysis provides insights into enhancer-mediated gene regulation

Jing Wang (4865)
Yue Zhao (186573)
Xiaofan Zhou (140325)
Scott Hiebert (5681903)
Qi Liu (33068)
Yu Shyr (28592)

August 2018

Figure S3. The effect of Hdac3 deletion on gene body transcription. (a) Heatmap of log2-transformed ...

Additional file 1: of Bortezomib treatment induces a higher mortality rate in lupus model mice with a higher disease activity

Tomoko Ikeda (816958)
Hiroshi Fujii (289510)
Masato Nose (1272312)
Yukiko Kamogawa (4351870)
Tsuyoshi Shirai (3938939)
Yuko Shirota (4351867)
Tomonori Ishii (186302)
Hideo Harigae (133506)

August 2017

is a table presenting significantly upregulated and downregulated genes in spleens of Bz-treated and...

Additional file 7: of Transcriptional profiling and biomarker identification reveal tissue specific effects of expanded ataxin-3 in a spinocerebellar ataxia type 3 mouse model

Lodewijk Toonen (5437412)
Maurice Overzier (5437403)
Melvin Evers (5437415)
Leticia Leon (3623615)
Sander van der Zeeuw (5437406)
Hailiang Mei (3404261)
Szymon Kielbasa (5437400)
Jelle Goeman (119419)
Kristina Hettne (390652)
Olafur Magnusson (524235)
Marion Poirel (5437409)
Alexandre Seyer (398024)
Peter ât Hoen (3427211)
Willeke van Roon-Mom (3431939)

June 2018

Figure S5. distribution of metabolite classes and lipid families identified from mass-spec analysis ...

Additional file 10: of Transcriptional profiling and biomarker identification reveal tissue specific effects of expanded ataxin-3 in a spinocerebellar ataxia type 3 mouse model

Lodewijk Toonen (5437412)
Maurice Overzier (5437403)
Melvin Evers (5437415)
Leticia Leon (3623615)
Sander van der Zeeuw (5437406)
Hailiang Mei (3404261)
Szymon Kielbasa (5437400)
Jelle Goeman (119419)
Kristina Hettne (390652)
Olafur Magnusson (524235)
Marion Poirel (5437409)
Alexandre Seyer (398024)
Peter ât Hoen (3427211)
Willeke van Roon-Mom (3431939)

June 2018

Table S2. Lipid classes altered at 4, 12 and 16Â months in SCA3 mice. Only lipid classes with at lea...

Additional file 6: of Transcriptional profiling and biomarker identification reveal tissue specific effects of expanded ataxin-3 in a spinocerebellar ataxia type 3 mouse model

Lodewijk Toonen (5437412)
Maurice Overzier (5437403)
Melvin Evers (5437415)
Leticia Leon (3623615)
Sander van der Zeeuw (5437406)
Hailiang Mei (3404261)
Szymon Kielbasa (5437400)
Jelle Goeman (119419)
Kristina Hettne (390652)
Olafur Magnusson (524235)
Marion Poirel (5437409)
Alexandre Seyer (398024)
Peter ‘t Hoen (3427337)
Willeke van Roon-Mom (3431939)

June 2018

Figure S4. number of reads and quality of blood RNA sequencing. A Number of reads obtained for each ...

Additional file 8: of Transcriptional profiling and biomarker identification reveal tissue specific effects of expanded ataxin-3 in a spinocerebellar ataxia type 3 mouse model

Lodewijk Toonen (5437412)
Maurice Overzier (5437403)
Melvin Evers (5437415)
Leticia Leon (3623615)
Sander van der Zeeuw (5437406)
Hailiang Mei (3404261)
Szymon Kielbasa (5437400)
Jelle Goeman (119419)
Kristina Hettne (390652)
Olafur Magnusson (524235)
Marion Poirel (5437409)
Alexandre Seyer (398024)
Peter ‘t Hoen (3427337)
Willeke van Roon-Mom (3431939)

June 2018

Figure S6. principal component analysis (PCA) of measured metabolites. Individual barcodes of mice a...

Additional file 1: Fig. S1. of Lentiviral vector-mediated overexpression of mutant ataxin-7 recapitulates SCA7 pathology and promotes accumulation of the FUS/TLS and MBNL1 RNA-binding proteins

Sandro Alves (376415)
Thibaut Marais (3488441)
Maria-Grazia Biferi (3488435)
Denis Furling (115627)
Martina Marinello (3488444)
Khalid El Hachimi (3488438)
Nathalie Cartier (3450368)
Merle Ruberg (777)
Giovanni Stevanin (115032)
Alexis Brice (41775)
Martine Barkats (402552)
Annie Sittler (3488447)

July 2016

Lentiviral-mediated overexpression of the Green Fluorescent Protein (GFP) in the mouse cerebellum. F...

Transcriptional profiling and biomarker identification reveal tissue specific effects of expanded ataxin-3 in a spinocerebellar ataxia type 3 mouse model

Toonen, L.J.A.
Overzier, M.
Evers, M.M.
Leon, L.G.
Zeeuw, S.A.J. van der
Mei, H.L.
Kielbasa, S.M.
Goeman, J.J.
Hettne, K.M.
Magnusson, O.T.
Poirel, M.
Seyer, A.
Hoen, P.A.C. 't
Roon-Mom, W.M.C. van

June 2018

Background: Spinocerebellar ataxia type 3 (SCA3) is a progressive neurodegenerative disorder caused ...

Additional file 1: of ZnT3 expression levels are down-regulated in the brain of Mcoln1 knockout mice

Jonathan Chacon (6517712)
Lauren Rosas (6517715)
Math Cuajungco (6517718)

March 2019

Materials and methods. Table S1. Basic demographics, sample IDs, and RNA-seq reads for each mouse sa...

Additional file 1: of The oncoprotein TBX3 is controlling severity in experimental arthritis

Samra Sardar (6197525)
Alish Kerr (6197528)
DaniĂŤlle Vaartjes (6197531)
Emilie Moltved (6197534)
Edita Karosiene (5392358)
Ramneek Gupta (437350)
Ăsa Andersson (6197537)

January 2019

Table S1. List of primers used for genotyping of mice. Table S2. List of primers for Tbx3 and Tbx5 s...

Additional file 3: Figure S3 of A brain-targeted, modified neurosin (kallikrein-6) reduces α-synuclein accumulation in a mouse model of multiple system atrophy

Brian Spencer (222903)
Elvira Valera (247143)
Edward Rockenstein (222885)
Margarita Trejo-Morales (710573)
Anthony Adame (222908)
Eliezer Masliah (2942)

September 2015

Real time PCR analysis of MBP and α-syn expression in MBP-α-syn tg mice. Real-time PCR analysis of g...

Additional file 1: of Transcriptome analysis of Shank3-overexpressing mice reveals unique molecular changes in the hypothalamus

Chunmei Jin (5705060)
Hyojin Kang (2848577)
Shinhyun Kim (5705063)
Yinhua Zhang (111234)
Yeunkum Lee (5705066)
Yoonhee Kim (414380)
Kihoon Han (260448)

November 2018

Materials and methods including information about mice, RNA sequencing and analysis, RNA purificatio...

Additional file 7: of Nascent RNA sequencing analysis provides insights into enhancer-mediated gene regulation

Jing Wang (4865)
Yue Zhao (186573)
Xiaofan Zhou (140325)
Scott Hiebert (5681903)
Qi Liu (33068)
Yu Shyr (28592)

August 2018

Table S3. Identified enhancers using Hdac3 WT and KO PRO-seq data derived from the mouse liver. (XLS...

Additional file 4: of Analysis of spinal and muscle pathology in transgenic mice overexpressing wild-type and ALS-linked mutant MATR3

Christina Moloney (3428585)
Sruti Rayaprolu (462055)
John Howard (3428567)
Susan Fromholt (3428582)
Hilda Brown (121300)
Matt Collins (157831)
Mariela Cabrera (3428573)
Colin Duffy (3428576)
Zoe Siemienski (426639)
Dave Miller (3428570)
David Borchelt (3428579)
Jada Lewis (160723)

December 2018

Figure S2. MATR3 is not robustly elevated in the spinal cords of MATR3WT and MATR3F115C mice. a Nort...

Additional file 3: of Bortezomib treatment induces a higher mortality rate in lupus model mice with a higher disease activity

Tomoko Ikeda (816958)
Hiroshi Fujii (289510)
Masato Nose (1272312)
Yukiko Kamogawa (4351870)
Tsuyoshi Shirai (3938939)
Yuko Shirota (4351867)
Tomonori Ishii (186302)
Hideo Harigae (133506)

August 2017

is a table presenting significantly increased or decreased genes among the proteasome ubiquitin path...

Additional file 4: of Nascent RNA sequencing analysis provides insights into enhancer-mediated gene regulation

Jing Wang (4865)
Yue Zhao (186573)
Xiaofan Zhou (140325)
Scott Hiebert (5681903)
Qi Liu (33068)
Yu Shyr (28592)

August 2018

Figure S3. The effect of Hdac3 deletion on gene body transcription. (a) Heatmap of log2-transformed ...

Additional file 1: of Bortezomib treatment induces a higher mortality rate in lupus model mice with a higher disease activity

Tomoko Ikeda (816958)
Hiroshi Fujii (289510)
Masato Nose (1272312)
Yukiko Kamogawa (4351870)
Tsuyoshi Shirai (3938939)
Yuko Shirota (4351867)
Tomonori Ishii (186302)
Hideo Harigae (133506)

August 2017

is a table presenting significantly upregulated and downregulated genes in spleens of Bz-treated and...

Additional file 7: of Transcriptional profiling and biomarker identification reveal tissue specific effects of expanded ataxin-3 in a spinocerebellar ataxia type 3 mouse model

Lodewijk Toonen (5437412)
Maurice Overzier (5437403)
Melvin Evers (5437415)
Leticia Leon (3623615)
Sander van der Zeeuw (5437406)
Hailiang Mei (3404261)
Szymon Kielbasa (5437400)
Jelle Goeman (119419)
Kristina Hettne (390652)
Olafur Magnusson (524235)
Marion Poirel (5437409)
Alexandre Seyer (398024)
Peter ât Hoen (3427211)
Willeke van Roon-Mom (3431939)

June 2018

Figure S5. distribution of metabolite classes and lipid families identified from mass-spec analysis ...

Additional file 10: of Transcriptional profiling and biomarker identification reveal tissue specific effects of expanded ataxin-3 in a spinocerebellar ataxia type 3 mouse model

Lodewijk Toonen (5437412)
Maurice Overzier (5437403)
Melvin Evers (5437415)
Leticia Leon (3623615)
Sander van der Zeeuw (5437406)
Hailiang Mei (3404261)
Szymon Kielbasa (5437400)
Jelle Goeman (119419)
Kristina Hettne (390652)
Olafur Magnusson (524235)
Marion Poirel (5437409)
Alexandre Seyer (398024)
Peter ât Hoen (3427211)
Willeke van Roon-Mom (3431939)

June 2018

Table S2. Lipid classes altered at 4, 12 and 16Â months in SCA3 mice. Only lipid classes with at lea...

Additional file 6: of Transcriptional profiling and biomarker identification reveal tissue specific effects of expanded ataxin-3 in a spinocerebellar ataxia type 3 mouse model

Lodewijk Toonen (5437412)
Maurice Overzier (5437403)
Melvin Evers (5437415)
Leticia Leon (3623615)
Sander van der Zeeuw (5437406)
Hailiang Mei (3404261)
Szymon Kielbasa (5437400)
Jelle Goeman (119419)
Kristina Hettne (390652)
Olafur Magnusson (524235)
Marion Poirel (5437409)
Alexandre Seyer (398024)
Peter ‘t Hoen (3427337)
Willeke van Roon-Mom (3431939)

June 2018

Figure S4. number of reads and quality of blood RNA sequencing. A Number of reads obtained for each ...

Additional file 8: of Transcriptional profiling and biomarker identification reveal tissue specific effects of expanded ataxin-3 in a spinocerebellar ataxia type 3 mouse model

Lodewijk Toonen (5437412)
Maurice Overzier (5437403)
Melvin Evers (5437415)
Leticia Leon (3623615)
Sander van der Zeeuw (5437406)
Hailiang Mei (3404261)
Szymon Kielbasa (5437400)
Jelle Goeman (119419)
Kristina Hettne (390652)
Olafur Magnusson (524235)
Marion Poirel (5437409)
Alexandre Seyer (398024)
Peter ‘t Hoen (3427337)
Willeke van Roon-Mom (3431939)

June 2018

Figure S6. principal component analysis (PCA) of measured metabolites. Individual barcodes of mice a...

Additional file 1: Fig. S1. of Lentiviral vector-mediated overexpression of mutant ataxin-7 recapitulates SCA7 pathology and promotes accumulation of the FUS/TLS and MBNL1 RNA-binding proteins

Sandro Alves (376415)
Thibaut Marais (3488441)
Maria-Grazia Biferi (3488435)
Denis Furling (115627)
Martina Marinello (3488444)
Khalid El Hachimi (3488438)
Nathalie Cartier (3450368)
Merle Ruberg (777)
Giovanni Stevanin (115032)
Alexis Brice (41775)
Martine Barkats (402552)
Annie Sittler (3488447)

July 2016

Lentiviral-mediated overexpression of the Green Fluorescent Protein (GFP) in the mouse cerebellum. F...

Transcriptional profiling and biomarker identification reveal tissue specific effects of expanded ataxin-3 in a spinocerebellar ataxia type 3 mouse model

Toonen, L.J.A.
Overzier, M.
Evers, M.M.
Leon, L.G.
Zeeuw, S.A.J. van der
Mei, H.L.
Kielbasa, S.M.
Goeman, J.J.
Hettne, K.M.
Magnusson, O.T.
Poirel, M.
Seyer, A.
Hoen, P.A.C. 't
Roon-Mom, W.M.C. van

June 2018

Background: Spinocerebellar ataxia type 3 (SCA3) is a progressive neurodegenerative disorder caused ...

Additional file 1: of ZnT3 expression levels are down-regulated in the brain of Mcoln1 knockout mice

Jonathan Chacon (6517712)
Lauren Rosas (6517715)
Math Cuajungco (6517718)

March 2019

Materials and methods. Table S1. Basic demographics, sample IDs, and RNA-seq reads for each mouse sa...

Additional file 1: of The oncoprotein TBX3 is controlling severity in experimental arthritis

Samra Sardar (6197525)
Alish Kerr (6197528)
DaniĂŤlle Vaartjes (6197531)
Emilie Moltved (6197534)
Edita Karosiene (5392358)
Ramneek Gupta (437350)
Ăsa Andersson (6197537)

January 2019

Table S1. List of primers used for genotyping of mice. Table S2. List of primers for Tbx3 and Tbx5 s...

Additional file 3: Figure S3 of A brain-targeted, modified neurosin (kallikrein-6) reduces α-synuclein accumulation in a mouse model of multiple system atrophy

Brian Spencer (222903)
Elvira Valera (247143)
Edward Rockenstein (222885)
Margarita Trejo-Morales (710573)
Anthony Adame (222908)
Eliezer Masliah (2942)

September 2015

Real time PCR analysis of MBP and α-syn expression in MBP-α-syn tg mice. Real-time PCR analysis of g...

Additional file 1: of Transcriptome analysis of Shank3-overexpressing mice reveals unique molecular changes in the hypothalamus

Chunmei Jin (5705060)
Hyojin Kang (2848577)
Shinhyun Kim (5705063)
Yinhua Zhang (111234)
Yeunkum Lee (5705066)
Yoonhee Kim (414380)
Kihoon Han (260448)

November 2018

Materials and methods including information about mice, RNA sequencing and analysis, RNA purificatio...

Additional file 7: of Nascent RNA sequencing analysis provides insights into enhancer-mediated gene regulation

Jing Wang (4865)
Yue Zhao (186573)
Xiaofan Zhou (140325)
Scott Hiebert (5681903)
Qi Liu (33068)
Yu Shyr (28592)

August 2018

Table S3. Identified enhancers using Hdac3 WT and KO PRO-seq data derived from the mouse liver. (XLS...

Additional file 4: of Analysis of spinal and muscle pathology in transgenic mice overexpressing wild-type and ALS-linked mutant MATR3

Christina Moloney (3428585)
Sruti Rayaprolu (462055)
John Howard (3428567)
Susan Fromholt (3428582)
Hilda Brown (121300)
Matt Collins (157831)
Mariela Cabrera (3428573)
Colin Duffy (3428576)
Zoe Siemienski (426639)
Dave Miller (3428570)
David Borchelt (3428579)
Jada Lewis (160723)

December 2018

Figure S2. MATR3 is not robustly elevated in the spinal cords of MATR3WT and MATR3F115C mice. a Nort...

Additional file 3: of Bortezomib treatment induces a higher mortality rate in lupus model mice with a higher disease activity

Tomoko Ikeda (816958)
Hiroshi Fujii (289510)
Masato Nose (1272312)
Yukiko Kamogawa (4351870)
Tsuyoshi Shirai (3938939)
Yuko Shirota (4351867)
Tomonori Ishii (186302)
Hideo Harigae (133506)

August 2017

is a table presenting significantly increased or decreased genes among the proteasome ubiquitin path...

Additional file 4: of Nascent RNA sequencing analysis provides insights into enhancer-mediated gene regulation

Jing Wang (4865)
Yue Zhao (186573)
Xiaofan Zhou (140325)
Scott Hiebert (5681903)
Qi Liu (33068)
Yu Shyr (28592)

August 2018

Figure S3. The effect of Hdac3 deletion on gene body transcription. (a) Heatmap of log2-transformed ...

Additional file 1: of Bortezomib treatment induces a higher mortality rate in lupus model mice with a higher disease activity

Tomoko Ikeda (816958)
Hiroshi Fujii (289510)
Masato Nose (1272312)
Yukiko Kamogawa (4351870)
Tsuyoshi Shirai (3938939)
Yuko Shirota (4351867)
Tomonori Ishii (186302)
Hideo Harigae (133506)

August 2017

is a table presenting significantly upregulated and downregulated genes in spleens of Bz-treated and...

Additional file 1: of Transcriptional profiling and biomarker identification reveal tissue specific effects of expanded ataxin-3 in a spinocerebellar ataxia type 3 mouse model

Abstract

Extracted data

Additional file 1: of Transcriptional profiling and biomarker identification reveal tissue specific effects of expanded ataxin-3 in a spinocerebellar ataxia type 3 mouse model

Abstract

Extracted data

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