is a table presenting significantly increased or decreased genes among the proteasome ubiquitin pathway, GADD45 signaling, and DNA damage induced 14-3-3 signaling. The genes which were significantly increased with Bz treatment and belong to the gene set of the proteasome ubiquitin pathway, and the genes which were significantly increased with Cyc treatment and belong to the gene set of GADD45 signaling and DNA damage induced 14-3-3 signaling were extracted with IPA analysis. (XLSX 10 kb
Figure S12. Proteasome inhibitors combined with fatty acid inhibition induce synergistic cell death....
Hepatocyte-specific Alk3 deficiency resulted in suppressed liver Alk3 and hepcidin mRNA expression. ...
A. REC1 cells were treated with vehicle or etoposide 4 μg/ml for 2–24 h and harvested. Cells (105 ce...
is a table presenting significantly upregulated and downregulated genes in spleens of Bz-treated and...
is a figure showing in-vitro induction of HSPA1A (HSP70) and HSPB1 (HSP27) expression in Bz-treated ...
is a figure showing the effect of Bz treatment on serum uric acid, calcium, and phosphate. Mice aged...
Figure S2. Knockdown of cyclin D1 and CDK4 antagonizes bortezomib-induced cell death. MCL cell line ...
Figure S3. Double knockdown of cyclin D1 and CDK4 antagonizes bortezomib-induced cell death similar ...
The glomerulus score. Table S2. The score of cell-infiltration level. Table S3. The primers used for...
Figure S10. Synergistic cell death after proteasome inhibition and simultaneous fatty acid inhibitio...
Figure S8. Autophagy inhibitors counteract palbociclib-mediated antagonism on bortezomib-induced cel...
Hepatic ferritin expression in Alk3fl/fl and Alk3fl/fl;Alb-Cre mice 14 days after BA challenge. Repr...
Figure S9. Co-treatment of bortezomib with autophagy inhibitors potentiates cell death induction. MC...
Hepatic hepcidin mRNA levels, red blood cell count, spleen to bodyweight ratio, and hepatic erfe mRN...
Spleen and duodenum mRNA levels in Alk3fl/fl and Alk3fl/fl;Alb-Cre mice 14 days after BA challenge. ...
Figure S12. Proteasome inhibitors combined with fatty acid inhibition induce synergistic cell death....
Hepatocyte-specific Alk3 deficiency resulted in suppressed liver Alk3 and hepcidin mRNA expression. ...
A. REC1 cells were treated with vehicle or etoposide 4 μg/ml for 2–24 h and harvested. Cells (105 ce...
is a table presenting significantly upregulated and downregulated genes in spleens of Bz-treated and...
is a figure showing in-vitro induction of HSPA1A (HSP70) and HSPB1 (HSP27) expression in Bz-treated ...
is a figure showing the effect of Bz treatment on serum uric acid, calcium, and phosphate. Mice aged...
Figure S2. Knockdown of cyclin D1 and CDK4 antagonizes bortezomib-induced cell death. MCL cell line ...
Figure S3. Double knockdown of cyclin D1 and CDK4 antagonizes bortezomib-induced cell death similar ...
The glomerulus score. Table S2. The score of cell-infiltration level. Table S3. The primers used for...
Figure S10. Synergistic cell death after proteasome inhibition and simultaneous fatty acid inhibitio...
Figure S8. Autophagy inhibitors counteract palbociclib-mediated antagonism on bortezomib-induced cel...
Hepatic ferritin expression in Alk3fl/fl and Alk3fl/fl;Alb-Cre mice 14 days after BA challenge. Repr...
Figure S9. Co-treatment of bortezomib with autophagy inhibitors potentiates cell death induction. MC...
Hepatic hepcidin mRNA levels, red blood cell count, spleen to bodyweight ratio, and hepatic erfe mRN...
Spleen and duodenum mRNA levels in Alk3fl/fl and Alk3fl/fl;Alb-Cre mice 14 days after BA challenge. ...
Figure S12. Proteasome inhibitors combined with fatty acid inhibition induce synergistic cell death....
Hepatocyte-specific Alk3 deficiency resulted in suppressed liver Alk3 and hepcidin mRNA expression. ...
A. REC1 cells were treated with vehicle or etoposide 4 μg/ml for 2–24 h and harvested. Cells (105 ce...