Materials and methods. Table S1. Basic demographics, sample IDs, and RNA-seq reads for each mouse sample. Table S2. Tabulated list of real-time qPCR primers used to validate specific RNA-seq data. Figure S1. RNA-seq coverage for exons within the major mouse Mcoln1 isoform. Figure S2. Baseline Ap3d1 transcript levels of individual brain tissues taken from Mcoln1â/â knockout (KO1-KO3, n = 3) and Mcoln1+/+ wild-type (WT1-WT3, n = 3) littermate control mice. (DOCX 5087 kb
Materials and methods including information about mice, RNA sequencing and analysis, RNA purificatio...
Table S1. Summary of RNA-Seq mapping results (Shank3 TG hypothalamus 10–12 wk). Table S2. List of DE...
Figure S1. Haplotype-based and broad-sense heritability estimates in CC mice. Figure S2. Phenotypic ...
Table S3. Tabulated list of differentially expressed genes between Mcoln1â/â KO and Mcoln1+/+ WT...
Figure S2. MATR3 is not robustly elevated in the spinal cords of MATR3WT and MATR3F115C mice. a Nort...
Figure S1. Dynamic RNA methylation in the developing mouse cerebellum. Figure S2. Comparison between...
Lentiviral-mediated overexpression of the Green Fluorescent Protein (GFP) in the mouse cerebellum. F...
Real time PCR analysis of MBP and α-syn expression in MBP-α-syn tg mice. Real-time PCR analysis of g...
Table S1. Primers used for qPCR validation of RNA sequencing results. (DOCX 13 kb
Figure S1. (A) Analysis the microarray data from GEO (GDS717), Znf179 mRNA expression in the whole b...
Table S2. Average body weights for lead MATR3WT and MATR3F115C lines. MATR3WT mice (lead line 1563) ...
Distribution of sequencing reads mapping with 0, 1, 2, 3, 4, or 5 mismatches to the reference genome...
Figure S4. number of reads and quality of blood RNA sequencing. A Number of reads obtained for each ...
Western blot analysis of A brain-derived neurotrophic factor (BDNF), B Growth associated protein 43 ...
Table S1. Mapping statistics of RNA-Seq data in various organs from CV and GF mice. Sample IDs, tota...
Materials and methods including information about mice, RNA sequencing and analysis, RNA purificatio...
Table S1. Summary of RNA-Seq mapping results (Shank3 TG hypothalamus 10–12 wk). Table S2. List of DE...
Figure S1. Haplotype-based and broad-sense heritability estimates in CC mice. Figure S2. Phenotypic ...
Table S3. Tabulated list of differentially expressed genes between Mcoln1â/â KO and Mcoln1+/+ WT...
Figure S2. MATR3 is not robustly elevated in the spinal cords of MATR3WT and MATR3F115C mice. a Nort...
Figure S1. Dynamic RNA methylation in the developing mouse cerebellum. Figure S2. Comparison between...
Lentiviral-mediated overexpression of the Green Fluorescent Protein (GFP) in the mouse cerebellum. F...
Real time PCR analysis of MBP and α-syn expression in MBP-α-syn tg mice. Real-time PCR analysis of g...
Table S1. Primers used for qPCR validation of RNA sequencing results. (DOCX 13 kb
Figure S1. (A) Analysis the microarray data from GEO (GDS717), Znf179 mRNA expression in the whole b...
Table S2. Average body weights for lead MATR3WT and MATR3F115C lines. MATR3WT mice (lead line 1563) ...
Distribution of sequencing reads mapping with 0, 1, 2, 3, 4, or 5 mismatches to the reference genome...
Figure S4. number of reads and quality of blood RNA sequencing. A Number of reads obtained for each ...
Western blot analysis of A brain-derived neurotrophic factor (BDNF), B Growth associated protein 43 ...
Table S1. Mapping statistics of RNA-Seq data in various organs from CV and GF mice. Sample IDs, tota...
Materials and methods including information about mice, RNA sequencing and analysis, RNA purificatio...
Table S1. Summary of RNA-Seq mapping results (Shank3 TG hypothalamus 10–12 wk). Table S2. List of DE...
Figure S1. Haplotype-based and broad-sense heritability estimates in CC mice. Figure S2. Phenotypic ...