<p>(A) The simulated current due to voltage-clamp method: voltage steps of ─140 to ─20 mV from a holding potential of ─10mV. (B) The simulated normalized current-voltage relationship curve (solid line) with superimposed experimental data (filled triangle) from [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0200712#pone.0200712.ref091" target="_blank">91</a>].</p
Mathematical models of ionic currents are used to study the electrophysiology of the heart, brain, g...
<p>A) Transmembrane potential (<i>V</i><sub><i>m</i></sub>) recorded during the action potential ups...
<p>(A) Equilibrium values of the gating variables for the Na (left) and K (right) channels. (B) Volt...
<p>(A) Normalised <i>I</i><sub>Kv6.1</sub> current trace in simulated voltage-clamp experiments. Cur...
<p>(A) DSM cell I<sub>BK</sub> model. Fig 4A represents the normalized simulated current-voltage cur...
<p>(A) The normalized I<sub>SK</sub> current with respect to Apamin in I<sub>SK</sub> model. (B) The...
<p>(A) Normalised <i>I</i><sub>T-type</sub> current trace in simulated voltage-clamp experiments. Cu...
<p>Current clamp response for a sample cell from the SS group. The sampled cell has 47 branches and ...
<p>(A) Normalised <i>I</i><sub>Kv3.4</sub> current trace in simulated voltage-clamp experiments. Cur...
<p>(A) Simulated voltage clamp traces of homomeric Kv7.1 channel from holding potential of −60 mV, w...
<p>(A) Voltage (V<sub>m</sub>)- and [Ca]<sub>i</sub>-dependence of steady state activation (<i>n</i>...
<p>The left figure shows the results for original holding voltage of −70 mV, while the right figure ...
<p><b>A</b> Steady-state activation and inactivation; <b>B</b> Time constants; <b>C</b> Current trac...
<p>A: Decay from peak of activation during a voltage-clamp of -10 mV in Nav 1.1 modelled channel. Th...
<p>(A) Voltage dependence of steady state activation (<i>m</i><sub>∞</sub>) and inactivation (<i>h</...
Mathematical models of ionic currents are used to study the electrophysiology of the heart, brain, g...
<p>A) Transmembrane potential (<i>V</i><sub><i>m</i></sub>) recorded during the action potential ups...
<p>(A) Equilibrium values of the gating variables for the Na (left) and K (right) channels. (B) Volt...
<p>(A) Normalised <i>I</i><sub>Kv6.1</sub> current trace in simulated voltage-clamp experiments. Cur...
<p>(A) DSM cell I<sub>BK</sub> model. Fig 4A represents the normalized simulated current-voltage cur...
<p>(A) The normalized I<sub>SK</sub> current with respect to Apamin in I<sub>SK</sub> model. (B) The...
<p>(A) Normalised <i>I</i><sub>T-type</sub> current trace in simulated voltage-clamp experiments. Cu...
<p>Current clamp response for a sample cell from the SS group. The sampled cell has 47 branches and ...
<p>(A) Normalised <i>I</i><sub>Kv3.4</sub> current trace in simulated voltage-clamp experiments. Cur...
<p>(A) Simulated voltage clamp traces of homomeric Kv7.1 channel from holding potential of −60 mV, w...
<p>(A) Voltage (V<sub>m</sub>)- and [Ca]<sub>i</sub>-dependence of steady state activation (<i>n</i>...
<p>The left figure shows the results for original holding voltage of −70 mV, while the right figure ...
<p><b>A</b> Steady-state activation and inactivation; <b>B</b> Time constants; <b>C</b> Current trac...
<p>A: Decay from peak of activation during a voltage-clamp of -10 mV in Nav 1.1 modelled channel. Th...
<p>(A) Voltage dependence of steady state activation (<i>m</i><sub>∞</sub>) and inactivation (<i>h</...
Mathematical models of ionic currents are used to study the electrophysiology of the heart, brain, g...
<p>A) Transmembrane potential (<i>V</i><sub><i>m</i></sub>) recorded during the action potential ups...
<p>(A) Equilibrium values of the gating variables for the Na (left) and K (right) channels. (B) Volt...