<p>Current clamp response for a sample cell from the SS group. The sampled cell has 47 branches and total dendritic area of 1284.67 μm2. (A) Voltage response to a current clamp of 10 pA amplitude. (B) FxI curve for the same cell model with inputs varying from 10 pA to 100 pA. The dashed lines indicate the minimum and maximum current amplitudes used to obtain the dynamic range of the cell.</p
<p>The graphs show the membrane potential of the PG cell model in response to a depolarizing current...
<p>(A) Mean voltage response (<i>n</i> = 4 cells) to a 30 Hz spike train. A hyperpolarizing current ...
<p>A, left, Schematic of the stimulus delivery and recording set-up under dynamic clamp. Two electro...
<p>In all cases, to calculate steady state firing frequencies, the input current was applied for 0.3...
<p>(A) The simulated current due to voltage-clamp method: voltage steps of ─140 to ─20 mV from a hol...
<p>Left panels: Typical examples of current waveforms recorded by AP-clamp; Right panels: I–V relati...
AbstractMathematical models are increasingly important in biology, and testability is becoming a cri...
(a) Cortical amplification of the LGN inputs. The excitatory currents (from the LGN only, as well as...
<p>(A) Response functions exemplified by normalized Hill functions with different Hill exponents <i...
<p><b>A</b>. Firing rate as a function of input current amplitude (f-I relationship) for a typical T...
<p>A) Example current-clamp traces in response to 500 ms positive somatic current injection in the C...
<p>(A) Normalised <i>I</i><sub>T-type</sub> current trace in simulated voltage-clamp experiments. Cu...
<p>(A) Plot of average stellate cell <i>f-I</i> curves using -5 ns (red), control (black) and 15 nS ...
<p>Comparison of experimental and simulated results of current-voltage behavior of the cells.</p
<p>(a) Black circles: minimum observed ISI for each active cell in network simulations of different ...
<p>The graphs show the membrane potential of the PG cell model in response to a depolarizing current...
<p>(A) Mean voltage response (<i>n</i> = 4 cells) to a 30 Hz spike train. A hyperpolarizing current ...
<p>A, left, Schematic of the stimulus delivery and recording set-up under dynamic clamp. Two electro...
<p>In all cases, to calculate steady state firing frequencies, the input current was applied for 0.3...
<p>(A) The simulated current due to voltage-clamp method: voltage steps of ─140 to ─20 mV from a hol...
<p>Left panels: Typical examples of current waveforms recorded by AP-clamp; Right panels: I–V relati...
AbstractMathematical models are increasingly important in biology, and testability is becoming a cri...
(a) Cortical amplification of the LGN inputs. The excitatory currents (from the LGN only, as well as...
<p>(A) Response functions exemplified by normalized Hill functions with different Hill exponents <i...
<p><b>A</b>. Firing rate as a function of input current amplitude (f-I relationship) for a typical T...
<p>A) Example current-clamp traces in response to 500 ms positive somatic current injection in the C...
<p>(A) Normalised <i>I</i><sub>T-type</sub> current trace in simulated voltage-clamp experiments. Cu...
<p>(A) Plot of average stellate cell <i>f-I</i> curves using -5 ns (red), control (black) and 15 nS ...
<p>Comparison of experimental and simulated results of current-voltage behavior of the cells.</p
<p>(a) Black circles: minimum observed ISI for each active cell in network simulations of different ...
<p>The graphs show the membrane potential of the PG cell model in response to a depolarizing current...
<p>(A) Mean voltage response (<i>n</i> = 4 cells) to a 30 Hz spike train. A hyperpolarizing current ...
<p>A, left, Schematic of the stimulus delivery and recording set-up under dynamic clamp. Two electro...