<p>(A) The normalized I<sub>SK</sub> current with respect to Apamin in I<sub>SK</sub> model. (B) The solid line represents the normalized simulated I<sub>SK</sub> current-voltage curve, where experimental data from murine DSM cell [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0200712#pone.0200712.ref040" target="_blank">40</a>] are superimposed (filled triangle). (C) The ATP dependent steady state activation parameter for K<sub>ATP</sub> channel model. (D) The normalized K<sub>ATP</sub> current-voltage relationship curve. The solid line represents result from our simulation where filled triangles are superimposed data from experiment [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0200712#pone...
<p>(<b>A</b>) Representative K<sub>v</sub> current traces obtained immediately after establishing wh...
<div><p>(A) and (C) show the β-cell responses in the islet, and (B) and (D) show the dispersed β-cel...
<p>(A,C) The Ex293 membrane model replicates (dotted line) the experimentally observed peak current-...
<p>(A) DSM cell I<sub>BK</sub> model. Fig 4A represents the normalized simulated current-voltage cur...
<p>(A) Apparent rate constant 2π<i>c</i> versus [ATP] plot, (B) active tension versus [ATP] plot, an...
<p>(A) The simulated current due to voltage-clamp method: voltage steps of ─140 to ─20 mV from a hol...
<p>(A) Voltage dependence of steady state activation (<i>n</i><sub>∞</sub>) of the modelled channel ...
<p><b>(</b>A) Simulated current–voltage relationship is shown in solid line against superimposed exp...
<p>(A) ATP-dependent concentration-response curves in the absence (black) and presence (red) of 3 μM...
<p>(A) Voltage (V<sub>m</sub>)- and [Ca]<sub>i</sub>-dependence of steady state activation (<i>n</i>...
<p>(A) Concentration-response relationships for glucose inhibition of K<sub>ATP</sub> conductance in...
<p>(A): APs produced by two sets of parameters (shown in <a href="http://www.plosone.org/article/inf...
<p>A: Simulation of electrical activity triggered by SGLT1-substrate uptake, corresponding to <i>α</...
A model for the kinetics of conformational transitions of ionotropic ATP receptors in pheochromocyto...
<p>(A) Normalised <i>I</i><sub>P2X4</sub> theoretical current traces for various ATP concentrations ...
<p>(<b>A</b>) Representative K<sub>v</sub> current traces obtained immediately after establishing wh...
<div><p>(A) and (C) show the β-cell responses in the islet, and (B) and (D) show the dispersed β-cel...
<p>(A,C) The Ex293 membrane model replicates (dotted line) the experimentally observed peak current-...
<p>(A) DSM cell I<sub>BK</sub> model. Fig 4A represents the normalized simulated current-voltage cur...
<p>(A) Apparent rate constant 2π<i>c</i> versus [ATP] plot, (B) active tension versus [ATP] plot, an...
<p>(A) The simulated current due to voltage-clamp method: voltage steps of ─140 to ─20 mV from a hol...
<p>(A) Voltage dependence of steady state activation (<i>n</i><sub>∞</sub>) of the modelled channel ...
<p><b>(</b>A) Simulated current–voltage relationship is shown in solid line against superimposed exp...
<p>(A) ATP-dependent concentration-response curves in the absence (black) and presence (red) of 3 μM...
<p>(A) Voltage (V<sub>m</sub>)- and [Ca]<sub>i</sub>-dependence of steady state activation (<i>n</i>...
<p>(A) Concentration-response relationships for glucose inhibition of K<sub>ATP</sub> conductance in...
<p>(A): APs produced by two sets of parameters (shown in <a href="http://www.plosone.org/article/inf...
<p>A: Simulation of electrical activity triggered by SGLT1-substrate uptake, corresponding to <i>α</...
A model for the kinetics of conformational transitions of ionotropic ATP receptors in pheochromocyto...
<p>(A) Normalised <i>I</i><sub>P2X4</sub> theoretical current traces for various ATP concentrations ...
<p>(<b>A</b>) Representative K<sub>v</sub> current traces obtained immediately after establishing wh...
<div><p>(A) and (C) show the β-cell responses in the islet, and (B) and (D) show the dispersed β-cel...
<p>(A,C) The Ex293 membrane model replicates (dotted line) the experimentally observed peak current-...