<i>Bhlhe40</i> KO mice do not have more-severe behavioral seizures.

<p>Animals were infused with 227ngs of KA and monitored for six hours. (A) Latency from infusion to first seizure, unpaired t-test p>0.05. (B) Total time seizing over the first 15 minutes, first 30 minutes, and full 6 hours, unpaired t-test p>0.05. (C) Latency from last seizure to the end of the six-hour monitoring period, unpaired t-test for each p>0.05. (D) Seizure scale for maximum seizure response for the first 15 minutes, first 30 minutes, and full 6 hours, unpaired t-test for each p>0.05. n = 6 for WT mice and n = 5 for <i>Bhlhe40</i> KO mice (Figs 2B and 2C), n = 6 for <i>Bhlhe40</i> KO mice (Figs 2A and 2D; including an animal that died during the monitoring period). Error bars are standard error of the mean.