<p>The 2 hour established SE profile, and the total numbers of spontaneous behavioral CS are given for each mouse. All mice in the mild group also had continuous stage-1 or 2 seizures for > 40 min during the 2 hours established SE (an example is shown in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0131705#pone.0131705.g001" target="_blank">Fig 1</a>). As in the severe SE group, there was no correlation between the amount of kainate given and the motor seizure latent period, and the number of CS episodes. Two mice did not become epileptic during first 4 weeks. eCSSS = electrographic CSSS index (in min); bCSSS = behavioral CSSS index (in min).</p
<p>A, The graph represents the percentage of mice with the generalized tonic-clonic seizures 1 h aft...
<p>The seizure frequencies (spontaneous recurrent seizures/day) in individual mice are represented b...
<p>(A) Data represent latency to severe stage 4/5 seizures in minutes (mean ± SEM) for GalR1 <sup>+/...
<p>The behavioral scoring (Racine scale stages from 1 to 5) for these mice during the 2 hours establ...
The C57BL/6J mouse as a model of seizure/epilepsy is challenging due to high mortality and huge vari...
<div><p>The C57BL/6J mouse as a model of seizure/epilepsy is challenging due to high mortality and h...
The C57BL/6J mouse as a model of seizure/epilepsy is challenging due to high mortality and huge vari...
Various etiological factors, such as head injury, chemical intoxication, tumors, and gene mutation, ...
<p><b>(A)</b> Neurodegeneration in CA3 of the hippocampus at 8 d after KA-induced status epilepticus...
<div><p>A refined kainate (KA) C57BL/6J mouse model of <i>status epilepticus</i> (SE) using a repeat...
A refined kainate (KA) C57BL/6J mouse model of status epilepticus (SE) using a repeated low dose (RL...
A refined kainate (KA) C57BL/6J mouse model of status epilepticus (SE) using a repeated low dose (RL...
A refined kainate (KA) C57BL/6J mouse model of status epilepticus (SE) using a repeated low dose (RL...
<p>A: A total of 82 mice were used for RLD of KA. About 95% of the animals reached stage-5 seizures ...
<p>The spikes/min column represents a minimum and a maximum number of spikes/min in an episode. The ...
<p>A, The graph represents the percentage of mice with the generalized tonic-clonic seizures 1 h aft...
<p>The seizure frequencies (spontaneous recurrent seizures/day) in individual mice are represented b...
<p>(A) Data represent latency to severe stage 4/5 seizures in minutes (mean ± SEM) for GalR1 <sup>+/...
<p>The behavioral scoring (Racine scale stages from 1 to 5) for these mice during the 2 hours establ...
The C57BL/6J mouse as a model of seizure/epilepsy is challenging due to high mortality and huge vari...
<div><p>The C57BL/6J mouse as a model of seizure/epilepsy is challenging due to high mortality and h...
The C57BL/6J mouse as a model of seizure/epilepsy is challenging due to high mortality and huge vari...
Various etiological factors, such as head injury, chemical intoxication, tumors, and gene mutation, ...
<p><b>(A)</b> Neurodegeneration in CA3 of the hippocampus at 8 d after KA-induced status epilepticus...
<div><p>A refined kainate (KA) C57BL/6J mouse model of <i>status epilepticus</i> (SE) using a repeat...
A refined kainate (KA) C57BL/6J mouse model of status epilepticus (SE) using a repeated low dose (RL...
A refined kainate (KA) C57BL/6J mouse model of status epilepticus (SE) using a repeated low dose (RL...
A refined kainate (KA) C57BL/6J mouse model of status epilepticus (SE) using a repeated low dose (RL...
<p>A: A total of 82 mice were used for RLD of KA. About 95% of the animals reached stage-5 seizures ...
<p>The spikes/min column represents a minimum and a maximum number of spikes/min in an episode. The ...
<p>A, The graph represents the percentage of mice with the generalized tonic-clonic seizures 1 h aft...
<p>The seizure frequencies (spontaneous recurrent seizures/day) in individual mice are represented b...
<p>(A) Data represent latency to severe stage 4/5 seizures in minutes (mean ± SEM) for GalR1 <sup>+/...