Figure S7. Tubb2b expression is significantly reduced in rSOX-4 mutant S16 cells. An MA plot of the mean expression of every gene (dots) against the log2-fold change is shown. The mean expression is calculated as the mean of the normalized counts across all samples, and the log2 fold change is relative to unmodified S16 cells. Genes above the red line (“0”) indicate higher expression in rSOX-4 mutant cells, and genes below the red line indicate lower expression in rSOX-4 mutant cells. Red dots indicate genes significantly differentially expressed between rSOX-4 mutant, and unmodified S16 cells (p < 0.05). Gmnn and Tubb2b are labeled and indicated by arrows. (AI 17314 kb
Figure S2. A) The stl365 allele was generated by a TALEN that resulted in one base pair insertion ca...
DNA binding sites associated with GM6-regulated genes. Genes differentially expressed at each time p...
(a) Changes in the mitochondrial OXPHOS system. Western blotting using OXPHOS detection cocktail ant...
Figure S2. Activity of a pilot set of putative regulatory elements on chromosomes 21, 22, and X in m...
Figure S5. rSOX-4 overlaps genomic features associated with enhancers. (A; Top) rSOX-4 (red box) ove...
Figure S6. CRISPR cuts all alleles in S16 cells. A wild-type specific diagnostic PCR was performed o...
Figure S4. TRANSFAC predictions of transcription factor binding sites within elements active in musc...
List of the 6197 SNPs residing within 6164 conserved, non-coding sequences. Columns 1 through 3 are ...
Abstract Background Identifying functional non-coding variation is critical for defining the genetic...
List of the pilot set of regions and SNPs from chromosome 21, 22, and X. Columns 1 through 3 are BED...
Figure S3. Seven regions display allele-specific differences in luciferase activity in muscle (C2C12...
Figure S1. A computational pipeline to identify putative regulatory SNPs. The human, mouse, and chic...
Figure S3. A-B) TEM of a cross-section of the PLLn at 5 dpf in MZ siblings. Myelinated axons are pse...
SOX10 regulates genes that inhibit glial cell differentiation in vivo. Primary Schwann cells were ex...
DNA motifs enriched in sequences upstream of GM6-regulated genes and known to interact with a protei...
Figure S2. A) The stl365 allele was generated by a TALEN that resulted in one base pair insertion ca...
DNA binding sites associated with GM6-regulated genes. Genes differentially expressed at each time p...
(a) Changes in the mitochondrial OXPHOS system. Western blotting using OXPHOS detection cocktail ant...
Figure S2. Activity of a pilot set of putative regulatory elements on chromosomes 21, 22, and X in m...
Figure S5. rSOX-4 overlaps genomic features associated with enhancers. (A; Top) rSOX-4 (red box) ove...
Figure S6. CRISPR cuts all alleles in S16 cells. A wild-type specific diagnostic PCR was performed o...
Figure S4. TRANSFAC predictions of transcription factor binding sites within elements active in musc...
List of the 6197 SNPs residing within 6164 conserved, non-coding sequences. Columns 1 through 3 are ...
Abstract Background Identifying functional non-coding variation is critical for defining the genetic...
List of the pilot set of regions and SNPs from chromosome 21, 22, and X. Columns 1 through 3 are BED...
Figure S3. Seven regions display allele-specific differences in luciferase activity in muscle (C2C12...
Figure S1. A computational pipeline to identify putative regulatory SNPs. The human, mouse, and chic...
Figure S3. A-B) TEM of a cross-section of the PLLn at 5 dpf in MZ siblings. Myelinated axons are pse...
SOX10 regulates genes that inhibit glial cell differentiation in vivo. Primary Schwann cells were ex...
DNA motifs enriched in sequences upstream of GM6-regulated genes and known to interact with a protei...
Figure S2. A) The stl365 allele was generated by a TALEN that resulted in one base pair insertion ca...
DNA binding sites associated with GM6-regulated genes. Genes differentially expressed at each time p...
(a) Changes in the mitochondrial OXPHOS system. Western blotting using OXPHOS detection cocktail ant...