S of embryos injected with G5UTR MO or G4 MO are shown (50 ng/embryo). Heart and liver precursors have been revealed by MLC2 (BCIP) and FOR1 (BM purple) probes, respectively. FOR1 was developed first. Ventral views are shown, with anterior at the top. Summary of frequencies with which the heart and liver phenotypes were observed for GATA5 MOs (B) and for GATA4 MOs (C). The doses of splicing MOs are indicated and for other MOs are as in Figs. 1 and 4.<p><b>Copyright information:</b></p><p>Taken from "GATA4 and GATA5 are essential for heart and liver development in embryos"</p><p>http://www.biomedcentral.com/1471-213X/8/74</p><p>BMC Developmental Biology 2008;8():74-74.</p><p>Published online 28 Jul 2008</p><p>PMCID:PMC2526999.</p><p></p
Gata4 expression was detected in wildtype mouse embryos by IHC at (A) E9.5, (B) E10.5 and (C) E11.5....
(A-I’) Histology of Gata4 transgenic mouse embryo heart at E14.5. Two panel images of each embryonic...
(A) Representative cardiac morphology of wild-type embryos injected with either wild-type smyd4 or s...
S of embryos injected with G5UTR MO or G4 MO are shown (50 ng/embryo). Heart and liver precursors ha...
S on heart and liver development at st. 37. 50 ng of G4 MO () or 10 ng of G6 MO cause heart and live...
H anti-HA antibody, is blocked by G4 but not by other MOs indicated. 1 ng of mRNA was injected into ...
H anti-HA antibody, is blocked by G5 but not by other MOs indicated. G5UTR MO ("G5U") does not affec...
H anti-HA antibody, is blocked by G5 but not by other MOs indicated. G5UTR MO ("G5U") does not affec...
showed reduced expression), but not GATA4 MOs (19/19 embryos for G4 (50 ng) and 22/22 embryos for G4...
Ected dose is indicated (in ng). 3–4–5, cDNA that contains exon 4 and regions of exons 3 and 5 deter...
Background: GATA factors 4/5/6 have been implicated in the development of the heart and endodermal ...
AbstractNormal heart development is orchestrated by a set of highly conserved transcription factors ...
(A-K’) Histology of Gata4 transgenic mouse embryonic heart at E14.5. The lower panels (A’-C’) and up...
Gata4 and Gata6 are closely related transcription factors that are essential for the development of ...
AbstractThe transcription factor Gata4 is essential for normal heart morphogenesis and regulates the...
Gata4 expression was detected in wildtype mouse embryos by IHC at (A) E9.5, (B) E10.5 and (C) E11.5....
(A-I’) Histology of Gata4 transgenic mouse embryo heart at E14.5. Two panel images of each embryonic...
(A) Representative cardiac morphology of wild-type embryos injected with either wild-type smyd4 or s...
S of embryos injected with G5UTR MO or G4 MO are shown (50 ng/embryo). Heart and liver precursors ha...
S on heart and liver development at st. 37. 50 ng of G4 MO () or 10 ng of G6 MO cause heart and live...
H anti-HA antibody, is blocked by G4 but not by other MOs indicated. 1 ng of mRNA was injected into ...
H anti-HA antibody, is blocked by G5 but not by other MOs indicated. G5UTR MO ("G5U") does not affec...
H anti-HA antibody, is blocked by G5 but not by other MOs indicated. G5UTR MO ("G5U") does not affec...
showed reduced expression), but not GATA4 MOs (19/19 embryos for G4 (50 ng) and 22/22 embryos for G4...
Ected dose is indicated (in ng). 3–4–5, cDNA that contains exon 4 and regions of exons 3 and 5 deter...
Background: GATA factors 4/5/6 have been implicated in the development of the heart and endodermal ...
AbstractNormal heart development is orchestrated by a set of highly conserved transcription factors ...
(A-K’) Histology of Gata4 transgenic mouse embryonic heart at E14.5. The lower panels (A’-C’) and up...
Gata4 and Gata6 are closely related transcription factors that are essential for the development of ...
AbstractThe transcription factor Gata4 is essential for normal heart morphogenesis and regulates the...
Gata4 expression was detected in wildtype mouse embryos by IHC at (A) E9.5, (B) E10.5 and (C) E11.5....
(A-I’) Histology of Gata4 transgenic mouse embryo heart at E14.5. Two panel images of each embryonic...
(A) Representative cardiac morphology of wild-type embryos injected with either wild-type smyd4 or s...